Both higher levels of physical activity and better sleep quality are important for cognitive health, with high-PA and good sleep quality showing the best global cognition and memory outcomes, supporting the need for dual-behavior interventions in aging populations.
Key Findings
Results
The interaction between physical activity and sleep quality was statistically significant for global cognition and memory.
Interaction was significant for global cognition (P=0.04) and memory (P=0.04)
Linear mixed effects models were used to assess joint associations
Study population comprised 498 older adults with average age of 70.96 years, 55.4% female
Participants were rural older Chinese adults from Sichuan, China
Results
The high physical activity and good sleep quality group had the best global cognitive function compared to the low-PA and poor sleep quality group.
High-PA and good sleep quality group: β=0.58, 95% CI: 0.29-0.92 for global cognition
High-PA and good sleep quality group: β=0.43, 95% CI: 0.23-0.64 for memory
Compared with the low-PA and poor sleep quality reference group
Any category of PA combined with sleep quality showed better global cognition function than the reference group
Results
Any combination of physical activity category with sleep quality was associated with better global cognitive function than low physical activity paired with poor sleep quality.
All PA and sleep quality combinations outperformed the low-PA/poor sleep quality group on global cognition
The beneficial association was observed across all PA categories when combined with sleep quality measures
Cognitive function was evaluated using the Telephone Interview for Cognitive Status (TICS)
Methods
The study was an observational analysis of an 8-week clustered randomized controlled trial with a 24-month follow-up among rural older Chinese adults.
Trial took place from May 2021 to May 2023 in Sichuan, China
498 older adults were included in the study population
Average participant age was 70.96 years
55.4% of participants were female
Stratified analysis was performed alongside linear mixed effects models
What This Means
This research suggests that among older adults in rural China, both getting enough physical activity and sleeping well are independently important for brain health — and that having both together provides the greatest benefit. Researchers followed nearly 500 older adults (average age around 71) over two years and found that those who were more physically active and also reported better sleep quality scored highest on tests of overall thinking ability and memory. Even people with only moderate physical activity or moderate sleep quality did better cognitively than those who were both inactive and sleeping poorly.
The study is notable because it examined how these two behaviors work together rather than looking at each one in isolation. The interaction between physical activity and sleep quality on cognitive outcomes was statistically significant, meaning the combined effect was more than just the sum of the two parts individually. This suggests that improving either behavior may help, but targeting both simultaneously could be the most effective strategy.
This research suggests that health programs aimed at protecting older adults' cognitive health should consider addressing both physical activity and sleep quality at the same time, rather than focusing on just one behavior. The findings support what the authors call 'dual-behavior interventions' for aging populations, though as an observational study it cannot prove that changing these behaviors directly causes better cognitive outcomes.
Li S, Li X, Yong C, Xiong Y, Liu W, Yue Z, et al.. (2026). Joint Associations of Physical Activity and Sleep Quality With Cognitive Function Among Older Adults in China.. Alzheimer disease and associated disorders. https://doi.org/10.1097/WAD.0000000000000713