Temperature and PM2.5 jointly influence short-term cardiovascular risk through nonlinear and subgroup-specific pathways, with temperature showing stronger short-term associations than local PM2.5 in West Florida.
Key Findings
Results
Temperature showed stronger short-term associations with cardiovascular hospital admissions than local PM2.5.
Analysis used daily hospital admissions for myocardial infarction, heart failure, and stroke within the BayCare Health System, 2017 to 2024.
Joint exposure-response relationships were estimated with distributed-lag generalized additive models with tensor-product interactions across lags 0 to 7 days.
Models adjusted for temporal trends, day of week, and copollutants.
Results
Among adults aged ≥65 years, myocardial infarction risk was higher at lower temperatures than at higher temperatures.
The abstract reports RR75/25 of 0.92 (95% CI, 0.89-0.95), comparing the 75th versus the 25th percentile of the temperature distribution.
An RR below 1 for the warmer percentile indicates lower risk at warmer temperatures relative to cooler ones.
Results
Heart failure showed a U-shaped temperature-risk relationship, with greater heat-related risk among younger adults and Black patients.
Younger adults: RR75/25 1.05 (95% CI, 1.02-1.09).
Black patients: RR75/25 1.05 (95% CI, 1.02-1.09).
Effect modification by age, sex, and race was examined.
Results
PM2.5 showed weaker overall associations with cardiovascular outcomes, with only a modest elevation in stroke risk among Black patients.
Stroke among Black patients: RR75/25 1.02 (95% CI, 0.96-1.08).
The reported confidence interval includes 1.
PM2.5 data were obtained from national monitoring networks.
Results
Joint temperature-PM2.5 exposure surfaces revealed outcome-specific nonlinear patterns, particularly for heart failure at higher temperature and PM2.5.
Tensor-product interaction terms were used to model joint exposure-response surfaces.
The patterns differed across myocardial infarction, heart failure, and stroke.
Background
The study characterized joint short-term temperature and PM2.5 effects on cardiovascular outcomes in a subtropical coastal region, West Florida, where they had not been well characterized.
Outcomes were hospital admissions for myocardial infarction, heart failure, and stroke from 2017 to 2024.
Daily mean temperature and PM2.5 were obtained from national monitoring networks.
Conclusions
The authors conclude that integrated climate and air-quality strategies are needed to reduce cardiovascular disparities.
Temperature and PM2.5 jointly influence short-term cardiovascular risk through nonlinear and subgroup-specific pathways.
What This Means
This study looked at hospital admissions for heart attack, heart failure, and stroke in the BayCare Health System in West Florida from 2017 to 2024. The researchers examined how daily temperature and fine particle air pollution (PM2.5), together, were linked to admissions over the following week.
Temperature appeared to matter more than local PM2.5 for short-term cardiovascular risk. Among adults 65 and older, heart attack risk was higher on cooler days than on warmer ones. Heart failure risk rose at both low and high temperatures (a U-shaped pattern), and heat-related heart failure risk was higher among younger adults and Black patients. PM2.5 showed weaker links overall, with only a small and statistically uncertain increase in stroke risk among Black patients.
This research suggests that heat, cold, and air pollution may affect heart health differently depending on the condition and the person's age and race. It points to a need for climate and air-quality planning to consider these differences. As an observational study of hospital admissions in one region, it shows associations rather than proof of cause.
Chen C, Shehub A, Orgul S, Davis M, Valina-Toth A. (2026). Joint Impacts of Ambient Air Pollution and Temperature on Cardiovascular Disease in West Florida.. Journal of the American Heart Association. https://doi.org/10.1161/JAHA.126.049988