Mental Health

Mediation role of artificial intelligence exposure in adverse childhood experiences: related mental health risks among college students.

TL;DR

Artificial intelligence usage mediates the relationship between adverse childhood experiences and mental health outcomes including loneliness, stress, anxiety, suicidal ideation, and depressive symptoms among college students, though the mediating effect proportions are small (2.6–5.4%).

Key Findings

Among college student participants, 794 (29%) reported exposure to adverse childhood experiences (ACEs).

  • Data were collected through questionnaire surveys from April to May 2025
  • Participants' psychosocial characteristics were assessed using validated scales measuring stress, anxiety, depression, ACEs status, loneliness, sleep quality, and suicidal ideation
  • Data analysis incorporated propensity score matching and causal mediation analysis

ACEs significantly increased loneliness, with AI usage mediating a small portion of this effect.

  • Total effect on loneliness was 0.24 (95% CI 0.18–0.31; P < 0.001)
  • The mediating effect proportion of AI usage on the ACEs–loneliness relationship was 5.2%

ACEs significantly increased stress symptoms, with AI usage mediating a small portion of this effect.

  • Total effect on stress was 0.71 (95% CI 0.56–0.88; P < 0.001)
  • The mediating effect proportion of AI usage on the ACEs–stress relationship was 4.4%

ACEs significantly increased anxiety symptoms, with AI usage mediating a small portion of this effect.

  • Total effect on anxiety symptoms was 0.65 (95% CI 0.51–0.81; P < 0.001)
  • The mediating effect proportion of AI usage on the ACEs–anxiety relationship was 4.9%

ACEs significantly increased suicidal ideation, with AI usage mediating a small portion of this effect.

  • Total effect on suicidal ideation was 0.07 (95% CI 0.06–0.09; P < 0.001)
  • The mediating effect proportion of AI usage on the ACEs–suicidal ideation relationship was 2.6%
  • This was the smallest mediating proportion observed across all mental health outcomes studied

ACEs significantly increased depressive symptoms, with AI usage mediating a small portion of this effect.

  • Total effect on depressive symptoms was 0.60 (95% CI 0.46–0.76; P < 0.001)
  • The mediating effect proportion of AI usage on the ACEs–depression relationship was 5.4%
  • This was the largest mediating proportion observed across all mental health outcomes studied

The greater the number of ACEs one has, the more pronounced the subsequent mental health issues become.

  • This dose-response relationship between ACE count and mental health severity is noted as a significant characteristic of ACE-related harm
  • The paper frames this as context for why mediating factors such as AI exposure are important to study

Social AI was identified as having a critical mediating role in mental health outcomes among ACE-affected individuals.

  • Mediation was detected across all five mental health outcomes: loneliness, stress, anxiety, suicidal ideation, and depressive symptoms
  • Mediating effect proportions ranged from 2.6% (suicidal ideation) to 5.4% (depressive symptoms)
  • Causal mediation analysis was used to establish these mediating relationships

What This Means

This research suggests that college students who experienced adverse childhood experiences (ACEs) — such as abuse, neglect, or household dysfunction during childhood — are at significantly greater risk for a range of mental health problems, including loneliness, stress, anxiety, thoughts of suicide, and depression. The study, conducted in spring 2025, surveyed college students and found that about 29% had experienced at least one ACE. Importantly, the researchers examined whether artificial intelligence use played any role in the pathway between childhood adversity and these mental health outcomes. The findings suggest that AI usage acts as a small but statistically significant mediator between ACEs and all five mental health outcomes studied. In other words, part of the reason ACEs are linked to worse mental health may be explained by differences in how affected individuals engage with AI tools. The mediating proportions were modest, ranging from about 2.6% for suicidal ideation to 5.4% for depressive symptoms, meaning that AI exposure accounts for a small but detectable share of the total effect of ACEs on mental health. This research matters because it highlights a potentially novel pathway through which technology — specifically AI — intersects with the long-term consequences of childhood trauma. As AI becomes more embedded in daily life, understanding how its use relates to mental health in vulnerable populations like ACE-affected individuals could inform how AI tools are designed or integrated into mental health support systems. The study relied on self-reported questionnaire data and used advanced statistical techniques (propensity score matching and causal mediation analysis) to try to account for confounding factors.

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Citation

Wang Y, Lv M, Huang R, Zhang J, Huang X, Yu Y, et al.. (2026). Mediation role of artificial intelligence exposure in adverse childhood experiences: related mental health risks among college students.. Scientific reports. https://doi.org/10.1038/s41598-026-37352-x