Cardiovascular

Mediterranean diet and its relationship with oral pathology.

TL;DR

Adherence to the Mediterranean Diet acts as a protective factor against both oral and systemic diseases, with statistically significant associations found between MD adherence and lower prevalence of cancer, cardiovascular disease, periodontal disease, dental caries, and improved salivary parameters.

Key Findings

Mediterranean Diet adherence was associated with significantly lower prevalence of cancer among study participants.

  • Study enrolled 232 patients assessed for MD adherence using the 'Mediterranean Diet Adherence Screener' questionnaire
  • Statistically significant difference in cancer prevalence between MD adherers and non-adherers (p = 0.045)
  • Multicenter population of adults with medical histories recorded

Mediterranean Diet adherence was associated with significantly lower prevalence of cardiovascular disease.

  • Statistically significant difference in cardiovascular disease prevalence between MD adherers and non-adherers (p = 0.02)
  • 232 total patients were assessed for both MD adherence and systemic conditions
  • Medical histories were recorded for all enrolled patients

Mediterranean Diet adherence was associated with better periodontal health as measured by periodontal disease stage.

  • Statistically significant correlation between periodontal disease stage and MD adherence (p = 0.009)
  • Intraoral examinations were performed on 43 patients from the adherence group and 30 patients from the non-adherence group
  • Periodontal disease stage was among the oral health parameters evaluated in the intraoral subsample

Mediterranean Diet adherence was associated with lower levels of dental caries as measured by DMFT (decayed, missing, and filled teeth) scores.

  • Statistically significant correlation between DMFT scores and MD adherence (p = 0.048)
  • Intraoral examination subsample included 43 adherent and 30 non-adherent patients
  • DMFT is a standard index measuring cumulative caries experience

Mediterranean Diet adherence was associated with higher stimulated salivary flow rate (stimulated sialometry).

  • Statistically significant correlation between stimulated sialometry and MD adherence (p = 0.002)
  • This was among the strongest statistical associations found in the study
  • Salivary flow was assessed in the intraoral examination subsample of 73 patients total

Mediterranean Diet adherence was associated with higher stimulated salivary pH.

  • Statistically significant correlation between stimulated pH and MD adherence (p = 0.019)
  • Stimulated salivary pH was one of four oral health parameters evaluated in the intraoral subsample
  • Both stimulated pH and stimulated sialometry were assessed, suggesting salivary function broadly correlates with MD adherence

The study used a two-group design comparing MD adherers and non-adherers on a range of oral and systemic health outcomes.

  • Total sample size was 232 patients enrolled with recorded medical histories
  • MD adherence was assessed using the validated 'Mediterranean Diet Adherence Screener' questionnaire
  • A randomly selected subsample of 73 patients (43 adherers, 30 non-adherers) underwent intraoral examination
  • The study was multicenter in design
  • Oral health parameters examined included dental caries (DMFT), periodontal disease stage, salivary flow, and salivary pH

What This Means

This research suggests that people who closely follow a Mediterranean Diet — which emphasizes fruits, vegetables, whole grains, legumes, fish, and olive oil — tend to have better oral and overall health compared to those who do not follow this dietary pattern. In a study of 232 adults across multiple clinics, researchers found that people adherent to the Mediterranean Diet had significantly lower rates of cancer and cardiovascular disease. Among a subgroup of 73 patients who received detailed dental examinations, those following the Mediterranean Diet also showed healthier gums (lower periodontal disease severity), fewer cavities, and better saliva quality — specifically higher salivary flow and less acidic saliva, both of which are protective for oral health. The findings are notable because they link diet not just to systemic conditions like heart disease, but also to specific measurable oral health indicators. Saliva plays a crucial role in protecting teeth and gums, so the finding that Mediterranean Diet followers had higher salivary flow and less acidic saliva may help explain why they also had fewer cavities and less gum disease. This research suggests that dietary patterns have wide-ranging effects on health that extend all the way to the mouth. This study adds to a growing body of evidence that the Mediterranean Diet may benefit multiple aspects of health simultaneously. The associations found are correlational rather than causal, and the intraoral examination subsample was relatively small (73 patients), so larger studies would be needed to confirm these findings. Nonetheless, this research suggests that promoting Mediterranean Diet adherence could be a meaningful public health strategy for reducing the burden of both oral diseases and chronic systemic conditions.

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Citation

Sánchez Cousiñoa D, Egido-Moreno S, González-Navarro B, López-Sánchez A, Fernández-Farhall J, Rodríguez-Molinero J, et al.. (2026). Mediterranean diet and its relationship with oral pathology.. Acta odontologica Scandinavica. https://doi.org/10.2340/aos.v85.46815