Body Composition

Muscle performance and bone density following a multi-intervention program with milk or soy milk supplementation in older adults: quasi-experimental study.

TL;DR

Exercise combined with nutrition education and protein supplementation, particularly milk, may be associated with favorable musculoskeletal outcomes including handgrip strength and bone mineral density in older adults.

Key Findings

All groups experienced significant improvements in walking speed following the 8-week multi-intervention program.

  • Quasi-experimental cluster-based study with 82 community-dwelling adults aged ≥60 years
  • Four groups: exercise alone (Group 1), exercise plus nutrition education (Group 2), exercise plus NE with milk supplementation (Group 3), exercise plus NE with soy milk supplementation (Group 4)
  • All groups engaged in resistance training 3 times per week for 8 weeks
  • Within-group analyses showed significant walking speed improvements across all four groups

The milk supplementation group (Group 3) showed significant improvements in handgrip strength and sit-to-stand performance.

  • Group 3 exhibited a mean change of +4.41 kg in handgrip strength
  • Group 3 exhibited a mean change of -1.94 seconds in 5-time sit-to-stand performance
  • These improvements were observed within-group from baseline to post-intervention

The milk supplementation group (Group 3) achieved greater gains in handgrip strength compared to other groups.

  • Group 3 achieved greater handgrip strength gains than Group 2 (exercise plus NE only) by -0.84 kg
  • Group 3 achieved greater handgrip strength gains than Group 4 (soy milk supplementation) by +0.52 kg
  • Between-group comparisons indicated milk supplementation provided additional benefit over NE alone and soy milk supplementation

The milk supplementation group (Group 3) showed a borderline significant improvement in total bone mineral density compared with the exercise-alone group.

  • Group 3 showed a total BMD change of +0.01 g/cm²
  • Group 1 (exercise alone) showed a total BMD change of -0.06 g/cm²
  • The difference was described as 'borderline significant'
  • BMD was measured using dual-energy X-ray absorptiometry (DXA)

Groups receiving nutrition education (Groups 2–4) exhibited greater increases in upper-limb bone mineral density compared with the exercise-alone group.

  • Group 2 (exercise plus NE) showed upper-limb BMD change of +0.04 g/cm²
  • Group 3 (exercise plus NE plus milk) showed upper-limb BMD change of +0.02 g/cm²
  • Group 4 (exercise plus NE plus soy milk) showed upper-limb BMD change of +0.01 g/cm²
  • Group 1 (exercise alone) showed upper-limb BMD change of -0.02 g/cm²
  • All three NE-receiving groups outperformed the exercise-alone group in upper-limb BMD

The study design was a quasi-experimental cluster-based trial with four distinct intervention groups in community-dwelling older adults.

  • 82 community-dwelling adults aged ≥60 years completed the intervention
  • 8-week duration with cluster-based group assignment
  • Body composition and physical performance were measured using DXA and standardized tests at baseline and after intervention
  • Registered at ClinicalTrials.gov as NCT06173271
  • Groups 2–4 received weekly nutrition education while Group 1 did not

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Citation

Liao T, Wang T, Lu M, Kuo H, Chen Y, Lin K, et al.. (2026). Muscle performance and bone density following a multi-intervention program with milk or soy milk supplementation in older adults: quasi-experimental study.. The journal of nutrition, health & aging. https://doi.org/10.1016/j.jnha.2026.100784