Muscle performance and bone density following a multi-intervention program with milk or soy milk supplementation in older adults: quasi-experimental study.
Liao T, Wang T, et al. • The journal of nutrition, health & aging • 2026
Exercise combined with nutrition education and protein supplementation, particularly milk, may be associated with favorable musculoskeletal outcomes including handgrip strength and bone mineral density in older adults.
Key Findings
Results
All groups experienced significant improvements in walking speed following the 8-week multi-intervention program.
Quasi-experimental cluster-based study with 82 community-dwelling adults aged ≥60 years
Four groups: exercise alone (Group 1), exercise plus nutrition education (Group 2), exercise plus NE with milk supplementation (Group 3), exercise plus NE with soy milk supplementation (Group 4)
All groups engaged in resistance training 3 times per week for 8 weeks
Within-group analyses showed significant walking speed improvements across all four groups
Results
The milk supplementation group (Group 3) showed significant improvements in handgrip strength and sit-to-stand performance.
Group 3 exhibited a mean change of +4.41 kg in handgrip strength
Group 3 exhibited a mean change of -1.94 seconds in 5-time sit-to-stand performance
These improvements were observed within-group from baseline to post-intervention
Results
The milk supplementation group (Group 3) achieved greater gains in handgrip strength compared to other groups.
Group 3 achieved greater handgrip strength gains than Group 2 (exercise plus NE only) by -0.84 kg
Group 3 achieved greater handgrip strength gains than Group 4 (soy milk supplementation) by +0.52 kg
Between-group comparisons indicated milk supplementation provided additional benefit over NE alone and soy milk supplementation
Results
The milk supplementation group (Group 3) showed a borderline significant improvement in total bone mineral density compared with the exercise-alone group.
Group 3 showed a total BMD change of +0.01 g/cm²
Group 1 (exercise alone) showed a total BMD change of -0.06 g/cm²
The difference was described as 'borderline significant'
BMD was measured using dual-energy X-ray absorptiometry (DXA)
Results
Groups receiving nutrition education (Groups 2–4) exhibited greater increases in upper-limb bone mineral density compared with the exercise-alone group.
Group 2 (exercise plus NE) showed upper-limb BMD change of +0.04 g/cm²
Group 3 (exercise plus NE plus milk) showed upper-limb BMD change of +0.02 g/cm²
Group 4 (exercise plus NE plus soy milk) showed upper-limb BMD change of +0.01 g/cm²
Group 1 (exercise alone) showed upper-limb BMD change of -0.02 g/cm²
All three NE-receiving groups outperformed the exercise-alone group in upper-limb BMD
Methods
The study design was a quasi-experimental cluster-based trial with four distinct intervention groups in community-dwelling older adults.
82 community-dwelling adults aged ≥60 years completed the intervention
8-week duration with cluster-based group assignment
Body composition and physical performance were measured using DXA and standardized tests at baseline and after intervention
Registered at ClinicalTrials.gov as NCT06173271
Groups 2–4 received weekly nutrition education while Group 1 did not
Liao T, Wang T, Lu M, Kuo H, Chen Y, Lin K, et al.. (2026). Muscle performance and bone density following a multi-intervention program with milk or soy milk supplementation in older adults: quasi-experimental study.. The journal of nutrition, health & aging. https://doi.org/10.1016/j.jnha.2026.100784