Novel adiposity indices and their role in identifying left ventricular hypertrophy among hypertensive individuals undergoing echocardiography.

All adiposity indices were significantly higher in individuals with left ventricular hypertrophy compared to those without.

• The study included 724 hypertensive adults who underwent standardized anthropometric and echocardiographic assessments.
• Adiposity indices assessed included BMI, waist circumference, ABSI, and BRI.
• Cross-sectional study design with standardized measurements.
• Left ventricular mass was indexed to both body surface area and height2.7.

BRI showed the strongest correlation with LVMH2.7 among all adiposity indices examined.

• BRI demonstrated a correlation coefficient of r = 0.423 with LVMH2.7.
• This correlation was particularly strong in women.
• BRI outperformed BMI, waist circumference, and ABSI in correlation analyses.
• Correlations were assessed for all four adiposity indices against LVM indexed to both body surface area and height2.7.

In multivariate analysis, BRI remained significantly associated with LVMH2.7 in both sexes, while ABSI was not independently associated in men.

• Multivariate analyses were performed controlling for relevant covariates.
• BRI maintained independent association with LVMH2.7 in both male and female subgroups.
• ABSI failed to show independent association with LVMH2.7 specifically in men.
• Sex-stratified analyses were conducted to evaluate differential associations.

ROC curve analysis demonstrated that BRI had the highest diagnostic accuracy for identifying LVH, outperforming BMI and ABSI.

• ROC curve analysis was used to assess diagnostic performance of all adiposity indices.
• BRI's superior diagnostic performance was especially evident when LVH was defined using LVMH2.7 indexing.
• BRI outperformed both traditional indices (BMI, waist circumference) and the novel index ABSI.
• Diagnostic performance comparisons were made across different LVH definitions based on LVM indexing method.

ABSI and BRI are novel adiposity indices that may better reflect cardiometabolic risk than BMI because they account for fat distribution.

• BMI is described as the most used measure of adiposity but does not account for fat distribution.
• A Body Shape Index (ABSI) and Body Roundness Index (BRI) are identified as novel alternatives.
• Their association with subclinical cardiac damage, particularly LVH, was previously unclear prior to this study.
• The study aimed to evaluate these indices in a large cohort of 724 hypertensive patients.