Body Composition

Nutritional status and taste impairment in adult patients with multiple sclerosis and dysphagia. A pilot study.

TL;DR

Patients with MS and dysphagia exhibit a high prevalence of overweight, inadequate dietary intake, and taste alterations, highlighting the need for comprehensive, multidisciplinary interventions involving speech therapy and nutritional support.

Key Findings

The majority of MS patients in this study presented with overweight or obesity.

  • 66.7% of patients presented with overweight or obesity
  • Median BMI was 28.1 kg/m²
  • Sample included 14 MS patients (7 women, 7 men; median age 46.9 ± 13.5 years) from Granada
  • Body composition was assessed using bioelectrical impedance analysis (TANITA)

The prevalence of mixed dysphagia was high among MS patients, with a significant difference by disease duration for mixed dysphagia specifically.

  • 71.4% of patients presented with mixed dysphagia
  • No significant differences in dysphagia prevalence were found according to disease duration overall, except for mixed dysphagia (p = 0.018)
  • Dysphagia risk was evaluated using the Yale Swallow protocol, TWST, and TOMASS protocols

More than 70% of MS patients had insufficient intake of energy, fibre, and key micronutrients.

  • Over 70% of patients had insufficient intake of energy, fibre, and micronutrients
  • Specific micronutrient deficiencies identified included calcium, iron, potassium, and magnesium
  • Dietary intake was recorded over 3 days using 24-hour recall and a food frequency questionnaire (FFQ)
  • Data were processed with Dietowin® software

Taste alterations were observed in the majority of MS patients, with sweetness perception most commonly affected.

  • 57.1% of patients experienced taste alterations overall
  • 78.6% of patients showed impaired perception of sweetness specifically
  • Basic taste perception was examined as part of the study protocol
  • Sample size was 14 MS patients

This was a pilot descriptive-analytical study of a small MS patient cohort in Granada assessing anthropometry, dysphagia, dietary intake, and taste perception.

  • Study included 14 MS patients (7 women, 7 men)
  • Median age was 46.9 ± 13.5 years
  • Anthropometry and body composition were assessed alongside dysphagia screening and taste evaluation
  • Multiple validated tools were used including the Yale Swallow protocol, TWST, and TOMASS protocols

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Citation

Franchina-Vergel N, Molina-López J, Planells E. (2026). Nutritional status and taste impairment in adult patients with multiple sclerosis and dysphagia. A pilot study.. Multiple sclerosis and related disorders. https://doi.org/10.1016/j.msard.2025.106909