In a 13-year single-center retrospective cohort of 60 pediatric patients undergoing peripheral vascular surgical interventions, favorable 30-day outcomes were observed with no mortality, major amputation, vascular reintervention, or clinically evident ischemic complication.
Key Findings
Results
Trauma was the most common overall etiology for pediatric peripheral vascular surgical intervention, accounting for 60% of cases.
36 of 60 patients (60.0%) had trauma as the etiology.
Iatrogenic lesions were the second most common cause (18/60, 30.0%).
Congenital vascular lesions accounted for the remaining cases (6/60, 10.0%).
The cohort included 60 consecutive patients over 13 years (January 2012 – December 2024) at a tertiary pediatric cardiovascular referral center.
Results
Marked age-related differences in etiology were observed, with iatrogenic lesions predominating in infants and trauma predominating in adolescents.
Among infants (0–2 years), 12 of 14 patients (85.7%) had iatrogenic lesions.
Among adolescents (>12 to <18 years), 27 of 30 patients (90.0%) had traumatic lesions.
The cohort was stratified into three age groups: infants (14/60, 23.3%), children (16/60, 26.7%), and adolescents (30/60, 50.0%).
Results
The upper extremity was the most frequently involved anatomic region, followed by the lower extremity and cervical vessels.
Upper extremity involvement was noted in 37 of 60 patients (61.7%).
Lower extremity involvement was noted in 21 of 60 patients (35.0%).
Cervical vessels were involved in 2 of 60 patients (3.3%).
Arterial lesions were the most common type of vascular involvement (40/60, 66.7%).
Results
Primary repair or end-to-end anastomosis was the most frequently performed operative procedure.
Primary repair or end-to-end anastomosis was performed in 23 of 60 patients (38.3%).
Embolectomy was performed in 12 of 60 patients (20.0%).
Ligation was performed in 10 of 60 patients (16.7%).
Autologous saphenous vein interposition grafting was performed in 8 of 60 patients (13.3%).
Results
There was no 30-day mortality, major amputation, vascular reintervention, or clinically evident ischemic complication in the entire cohort.
All 60 patients completed 30-day clinical and Doppler ultrasonographic assessment.
Zero cases of 30-day mortality were recorded.
Zero cases of major amputation or vascular reintervention were recorded.
Zero cases of clinically evident ischemic complication were recorded within the 30-day follow-up period.
Results
Adolescents represented the largest age group in this pediatric vascular surgical cohort.
Adolescents (>12 to <18 years) comprised 30 of 60 patients (50.0%).
Children (3–12 years) comprised 16 of 60 patients (26.7%).
Infants (0–2 years) comprised 14 of 60 patients (23.3%).
The study was a retrospective single-center cohort design over 13 years.
Discussion
The authors identify the need for multicenter studies with standardized long-term follow-up to evaluate late vascular patency, growth-related changes, and functional outcomes.
The paper notes that published experience in pediatric peripheral vascular surgery remains limited to small institutional series or trauma-focused cohorts.
The authors highlight that growth-related changes in vascular reconstructions represent an important unanswered question.
The current study's follow-up was limited to 30 days, leaving long-term outcomes unaddressed.
The authors call for individualized decision-making and timely referral to specialized multidisciplinary centers based on age-specific etiologic patterns.
What This Means
This research examined 13 years of surgical cases at a specialized children's heart and vascular center in Turkey, focusing on children under 18 who needed surgery on peripheral blood vessels (those outside the heart and major chest vessels). Over that period, 60 children were treated, and the study found that the causes of injury differed strongly by age: very young children (infants up to age 2) were most commonly injured by medical procedures such as catheter placements, while teenagers were most often injured by accidents or trauma. The upper arm and forearm were the most commonly affected areas, and most injuries involved arteries rather than veins.
The surgical team used a variety of repair techniques, most commonly directly stitching the vessel back together or reconnecting cut ends, followed by procedures to remove blood clots and, less frequently, using a piece of vein from the patient's own leg to bridge a gap in a damaged vessel. Importantly, none of the 60 patients died, lost a limb, needed a second vascular operation, or showed signs of tissue damage from poor blood flow within 30 days of surgery — a strong short-term outcome for a complex patient population.
This research suggests that children can undergo peripheral vascular surgery with very good short-term results when treated at specialized centers, and that awareness of the different causes of vascular injury in different age groups can help doctors respond quickly and appropriately. However, the study only tracked patients for 30 days, so questions remain about how these repairs hold up as children grow and whether blood vessels remain open over many years. Larger studies across multiple hospitals with longer follow-up are needed to fully understand the long-term effects of these repairs in growing children.