Perceived control may act as a resilience factor, with a high-control class demonstrating more flexible cortisol secretion, greater bilateral posterior insula activation during psychosocial stress, less helplessness, fewer psychosomatic symptoms, and a less external locus of control compared to a low-control class.
Key Findings
Results
Growth mixture modeling of perceived control during an uncontrollable stress task identified two distinct classes: a high-control class and a low-control class.
116 male participants aged 18-30 were included in the study.
Perceived control was measured during an uncontrollable stress task separate from the main psychosocial stress task.
Growth mixture modeling (GMM) was used to classify participants into latent trajectory classes based on their perceived control responses.
The two-class solution yielded a high-control class and a low-control class.
Results
The high-control class experienced less helplessness during the uncontrollability task compared to the low-control class.
Helplessness was assessed as an affective response during the uncontrollable stress task.
This difference was reported as a key distinguishing feature between the two classes.
The finding is consistent with the interpretation that perceived control buffers feelings of helplessness when facing uncontrollable stressors.
Results
The high-control class demonstrated more flexible cortisol responses to a psychosocial stressor compared to the low-control class.
Cortisol levels were assessed as an endocrine stress response during a psychosocial stress task (distinct from the uncontrollability task).
The cortisol response pattern in the high-control class was characterized as 'more flexible responses to psychosocial stress.'
Participants underwent a psychosocial stress task while cortisol was measured.
Results
The high-control class showed greater activation of the bilateral posterior insula during psychosocial stress compared to the low-control class.
Neural responses were assessed via functional magnetic resonance imaging (fMRI) during the psychosocial stress task.
The bilateral posterior insula was specifically identified as showing differential activation between the two control classes.
This activation pattern was interpreted as reflecting more flexible stress processing in the high-control class.
Results
The high-control class reported fewer psychosomatic symptoms and a less external locus of control than the low-control class.
General mental health was assessed via self-report measures.
Psychosomatic symptoms were among the mental health outcomes showing significant differences between the two classes.
Locus of control was also assessed and differed between classes, with the high-control class showing a less external locus of control.
These findings link perceived control during a laboratory task to broader indices of mental health.
Methods
The study design assessed stress responses across neural, endocrine, and affective domains in response to a psychosocial stressor in a male-only sample.
Sample consisted of 116 male participants aged 18-30.
Stress responses were assessed via fMRI, cortisol levels, and affective state questionnaires.
Participants completed both a psychosocial stress task and a separate uncontrollable stress task.
The restriction to male participants limits generalizability; the authors note the need for further research.
Meier J, Kollmann B, Meine L, Meyer B, Yuen K, Stork M, et al.. (2026). Perceived control as a resilience factor: associations with neural, physiological and affective stress responses and mental health.. Translational psychiatry. https://doi.org/10.1038/s41398-025-03786-6