Cardiovascular

Performance of the Lausanne Ischemic Stroke Pathway prehospital triage system in identifying acute reperfusion candidates: a quality-control study.

TL;DR

Undertriage and overtriage rates in the Lausanne Ischemic Stroke Pathway were relatively high, but both were reduced by the CMT call, highlighting the added value of a second expert assessment step with a higher level of expertise.

Key Findings

Of 1071 included patients, the EMS phone-contacted the coordinated medical team (CMT) for 937 (87.5%).

  • Retrospective single-centre quality-control study at a Swiss university-based stroke centre, 1 January 2019 to 31 May 2022.
  • Inclusion: patients aged ≥18 years for whom the EMS called the CMT, or patients with AIS eligible for acute reperfusion managed by the EMS.

440 of 1071 patients (41%) had an acute ischaemic stroke eligible for acute reperfusion.

  • The remaining patients did not have an AIS eligible for reperfusion and constituted the overtriaged group or other categories.

The overall system undertriage rate was 30%.

  • 133 patients with an AIS eligible for acute reperfusion did not have the stroke pathway activated, among the 440 eligible patients.

Undertriage was 21% at the EMS step and 11% at the CMT step.

  • The CMT's lower undertriage rate indicates that the second expert assessment reduced missed reperfusion candidates relative to EMS alone.

Overtriage was 63% for the EMS and 57% for the CMT.

  • Overtriage was therefore also reduced, though modestly, by the CMT call.
  • Overtriage and undertriage were both described by the authors as relatively high.

The main alternative diagnoses among overtriaged patients were seizures (14%), intracranial haemorrhages (9.9%) and functional disorders (6.5%).

  • Identification of alternative diagnoses was a secondary outcome.
  • The authors suggest better prehospital identification of alternative diagnoses such as seizures or functional disorders could help to better classify patients.

The authors conclude that the second expert assessment step by the CMT adds value to prehospital triage.

  • Both undertriage and overtriage were reduced by the CMT call, which involves a higher level of expertise (neurologist plus emergency physician).

What This Means

This study looked at how well a Swiss prehospital system in Lausanne identifies stroke patients who could receive emergency treatments to restore blood flow to the brain. Paramedics use specific criteria and, when they suspect such a stroke, call a coordinated medical team including a neurologist and an emergency physician, who can activate the hospital's stroke pathway. The researchers reviewed 1071 patients over about three and a half years. About 41% of the patients actually had a stroke eligible for these treatments. The system missed 30% of those eligible patients, meaning the stroke pathway was not activated for them. Paramedics alone missed 21%, and after the team's review the missed rate was 11%. At the same time, many patients flagged as possible candidates were not: 63% of paramedic flags and 57% of team-confirmed flags were false alarms. Among false alarms, seizures, brain bleeds and functional disorders were the most common actual diagnoses. This research suggests that a second expert review by a neurologist and emergency physician helps both catch more eligible patients and reduce false alarms. It also suggests that better recognition of conditions that mimic stroke, such as seizures and functional disorders, might further improve how patients are sorted before reaching the hospital. The study was retrospective and done at a single centre, so results may not apply everywhere.

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Citation

Bianchi C, Michel P, Strambo D, Dami F, Carron P, Pasquier M. (2026). Performance of the Lausanne Ischemic Stroke Pathway prehospital triage system in identifying acute reperfusion candidates: a quality-control study.. Swiss medical weekly. https://doi.org/10.57187/5264