A 58-year-old man developed a rare combination of left ventricular apical pseudoaneurysm with post-infarction ventricular septal rupture two months after untreated anterior myocardial infarction, successfully treated with aneurysmectomy, septal defect closure, and coronary artery bypass grafting.
Key Findings
Background
A patient developed a large left ventricular apical pseudoaneurysm combined with post-infarction ventricular septal rupture following untreated anterior myocardial infarction.
The patient was a 58-year-old man
The mechanical complications developed approximately two months after the initial myocardial infarction
The anterior myocardial infarction was untreated (no reperfusion therapy was administered)
The ventricular septal rupture extended into the right ventricle, resulting in a significant left-to-right shunt
Background
The patient presented with progressive heart failure as the clinical manifestation of the combined mechanical complications.
Heart failure developed over a two-month period following the index myocardial infarction
The presentation occurred in the context of delayed or absent reperfusion therapy
The combination of pseudoaneurysm and ventricular septal rupture is described as rare and life-threatening
Methods
Multimodality imaging was used to diagnose and characterize the structural complications.
Imaging demonstrated a large left ventricular apical pseudoaneurysm
Post-infarction ventricular septal rupture into the right ventricle was identified
The report emphasizes the 'essential role of imaging in diagnosis and surgical planning'
Multimodality imaging was required to fully characterize the lesions
Results
The patient underwent successful surgical intervention addressing all identified mechanical complications.
Surgery included aneurysmectomy (resection of the pseudoaneurysm)
Closure of the ventricular septal defect was performed
Coronary artery bypass grafting was also carried out
The surgical outcome is described as successful
Discussion
The simultaneous occurrence of left ventricular pseudoaneurysm and post-infarction ventricular septal rupture represents a rare combination of mechanical complications.
The report describes this combination as rare and complex
The case is presented as contributing 'to the understanding of structural sequelae of myocardial infarction'
Delayed reperfusion is highlighted as a contributing factor to these mechanical complications
The case underscores that mechanical complications may still occur despite advances in reperfusion therapy
Yerekesh B, Nurumova Z, Assylbekova A, Tuleutayev R, Gebel D, Sani L, et al.. (2026). Post-infarction left ventricular pseudoaneurysm with septal rupture: a case report.. The Pan African medical journal. https://doi.org/10.11604/pamj.2025.52.160.50101