Cardiovascular

Post-infarction left ventricular pseudoaneurysm with septal rupture: a case report.

TL;DR

A 58-year-old man developed a rare combination of left ventricular apical pseudoaneurysm with post-infarction ventricular septal rupture two months after untreated anterior myocardial infarction, successfully treated with aneurysmectomy, septal defect closure, and coronary artery bypass grafting.

Key Findings

A patient developed a large left ventricular apical pseudoaneurysm combined with post-infarction ventricular septal rupture following untreated anterior myocardial infarction.

  • The patient was a 58-year-old man
  • The mechanical complications developed approximately two months after the initial myocardial infarction
  • The anterior myocardial infarction was untreated (no reperfusion therapy was administered)
  • The ventricular septal rupture extended into the right ventricle, resulting in a significant left-to-right shunt

The patient presented with progressive heart failure as the clinical manifestation of the combined mechanical complications.

  • Heart failure developed over a two-month period following the index myocardial infarction
  • The presentation occurred in the context of delayed or absent reperfusion therapy
  • The combination of pseudoaneurysm and ventricular septal rupture is described as rare and life-threatening

Multimodality imaging was used to diagnose and characterize the structural complications.

  • Imaging demonstrated a large left ventricular apical pseudoaneurysm
  • Post-infarction ventricular septal rupture into the right ventricle was identified
  • The report emphasizes the 'essential role of imaging in diagnosis and surgical planning'
  • Multimodality imaging was required to fully characterize the lesions

The patient underwent successful surgical intervention addressing all identified mechanical complications.

  • Surgery included aneurysmectomy (resection of the pseudoaneurysm)
  • Closure of the ventricular septal defect was performed
  • Coronary artery bypass grafting was also carried out
  • The surgical outcome is described as successful

The simultaneous occurrence of left ventricular pseudoaneurysm and post-infarction ventricular septal rupture represents a rare combination of mechanical complications.

  • The report describes this combination as rare and complex
  • The case is presented as contributing 'to the understanding of structural sequelae of myocardial infarction'
  • Delayed reperfusion is highlighted as a contributing factor to these mechanical complications
  • The case underscores that mechanical complications may still occur despite advances in reperfusion therapy

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Citation

Yerekesh B, Nurumova Z, Assylbekova A, Tuleutayev R, Gebel D, Sani L, et al.. (2026). Post-infarction left ventricular pseudoaneurysm with septal rupture: a case report.. The Pan African medical journal. https://doi.org/10.11604/pamj.2025.52.160.50101