Potentially traumatic life events and mental health conditions. Identifying the role of resilience in a cross-sectional study from Northwestern Germany.
Sisenop F, Arndt S, et al. • International journal of public health • 2026
Cumulative and type of potentially traumatic life events (especially war/conflict related) were associated with worse mental health, and resilience moderated associations with depression at lower resilience levels.
Key Findings
Results
Depression was reported by 16.1% and anxiety by 11.9% of the study participants.
Sample consisted of 354 adults in Northwestern Germany in a cross-sectional population-based design.
Depression was assessed using PHQ-9; 57 participants (16.1%) met criteria.
Anxiety was reported by 42 participants (11.9%).
The study was conducted in a rural area of Northwestern Germany.
Results
Four clusters of potentially traumatic events (PTEs) were identified on a conceptual basis with varying prevalence.
Accidental/injury events were the most common cluster (n = 300, 84.7%).
Loss/life-threatening events affected nearly as many participants (n = 299, 84.5%).
Victimization events were reported by 218 participants (61.6%).
War/conflict-related events were the least common cluster (n = 88, 24.9%).
PTE clusters were identified using the Life Events Checklist for DSM-5 (LEC-5).
Results
War/conflict-related events were significantly associated with higher depression scores.
The association between war/conflict-related PTEs and depression was statistically significant (B = 1.330, 95% CI: 0.013, 2.647).
This finding was identified through linear regression analysis.
Depression was measured using the PHQ-9.
War/conflict-related events were the least prevalent cluster but showed the most notable link to depression.
Results
Cumulative exposure to PTEs was associated with worse mental health outcomes.
Linear regression analysis was used to investigate the association between quantity of PTEs and mental health.
Both cumulative number and specific type of PTEs were associated with worse mental health.
The study assessed both depression and anxiety as mental health outcomes.
Resilience was measured using the Brief Resilience Scale (BRS).
Results
Resilience moderated the association between PTEs and depression, particularly at lower resilience levels.
Resilience was tested as a moderator in the relationship between PTEs and mental health conditions.
The moderation effect of resilience was specifically observed at lower resilience levels.
Resilience was assessed using the Brief Resilience Scale (BRS).
The moderating role of resilience was demonstrated through moderation analysis within the linear regression framework.
The moderating effect was specific to depression rather than anxiety.
Background
There is limited existing evidence on the association between quantity and type of PTEs and mental health specifically in rural areas.
The study was motivated by a gap in the literature regarding PTEs and mental health in rural populations.
The study population was drawn from Northwestern Germany, a predominantly rural region.
The cross-sectional design with n = 354 adults addressed this identified gap.
Sociodemographic factors were also assessed as part of the study.
What This Means
This research examined how potentially traumatic life events (PTEs) — such as accidents, losses, victimization, and war-related experiences — relate to depression and anxiety in a sample of 354 adults from a rural area in Northwestern Germany. The study found that over 84% of participants had experienced accidental or life-threatening events, while about 25% had experienced war or conflict-related events. Depression was present in about 1 in 6 participants, and anxiety in about 1 in 8. People who had experienced war or conflict-related events had significantly higher depression scores compared to others, and experiencing more types of traumatic events overall was linked to worse mental health.
The study also found that resilience — a person's ability to recover from adversity — played an important role in the relationship between traumatic experiences and depression. Specifically, resilience appeared to buffer the negative effects of PTEs on depression, but this protective effect was most apparent among people with lower levels of resilience. This suggests that those with already limited resilience may be especially vulnerable to the mental health effects of traumatic experiences.
This research suggests that both the number and specific type of traumatic life events matter for mental health, with war and conflict experiences being particularly harmful. It also highlights that building or supporting resilience in communities, especially in rural areas that may have fewer mental health resources, could be an important avenue for protecting mental health among people who have faced traumatic events. The findings point to a need for targeted mental health support for individuals with histories of war-related trauma and low resilience.
Sisenop F, Arndt S, Behr K, Chatarajupalli P, Schäfer I, Lindert J. (2026). Potentially traumatic life events and mental health conditions. Identifying the role of resilience in a cross-sectional study from Northwestern Germany.. International journal of public health. https://doi.org/10.3389/ijph.2026.1609376