Dietary Supplements

Prevalence and Correlates of Dietary Supplement Use Among Italian University Students: A Cross-Sectional Study.

TL;DR

A cross-sectional survey of 2001 Italian university students found a 55.7% lifetime prevalence of dietary supplement use, with self-rated knowledge as the strongest correlate, while 34.6% of users reported adverse symptoms, highlighting a gap between perceived knowledge and actual safety outcomes.

Key Findings

The lifetime prevalence of dietary supplement use among Italian university students was 55.7%.

  • Survey conducted among 2001 students at the University of Catania.
  • Study used EU regulatory definitions to classify dietary supplements.
  • Design was cross-sectional, capturing lifetime (ever-use) prevalence rather than current use.
  • The study employed multivariable logistic regression models to identify associated factors.

Self-rated knowledge of dietary supplements was the strongest correlate of lifetime supplement use.

  • Moderately informed participants had an OR of 4.02 (95% CI: 3.17–5.10) compared to those with low self-rated knowledge.
  • Well or completely informed participants had an OR of 4.70 (95% CI: 3.44–6.42).
  • The odds were described as 'comparable' between moderately and well/completely informed groups, suggesting a plateau effect.
  • This finding indicates a gap between high self-rated knowledge and the frequency of self-reported side effects.

Information sources were significantly associated with increased odds of dietary supplement use.

  • Receiving information from health professionals was associated with increased odds of use (OR = 2.19; 95% CI: 1.59–3.02).
  • Receiving information from friends was also associated with increased odds of use (OR = 1.91; 95% CI: 1.37–2.65).
  • The study noted that DS use is 'often influenced by non-institutional information.'
  • Both professional and peer information sources independently predicted use in multivariable models.

Enrollment in scientific fields of study was associated with increased odds of dietary supplement use.

  • Students in scientific fields had an OR of 1.70 (95% CI: 1.23–2.35) for lifetime supplement use compared to non-scientific fields.
  • This association remained significant after multivariable adjustment.
  • Field of study was identified as a behavioral correlate alongside information sources and self-rated knowledge.

More than one-third of dietary supplement users reported at least one adverse symptom temporally associated with supplement intake.

  • 34.6% of users reported at least one symptom temporally associated with supplement intake.
  • The study characterized these as 'self-reported adverse effects.'
  • The high rate of adverse symptom reports was interpreted as evidence of a gap between high self-rated knowledge and safe supplementation practices.
  • Consumption frequency and product diversity were evaluated in relation to safety outcomes.

The majority of students expressed receptivity toward institutional educational meetings on dietary supplements.

  • 74.3% of the total sample welcomed institutional meetings on dietary supplements.
  • Among supplement users, favourability toward informative meetings was significantly associated with daily supplement intake (OR = 1.97; 95% CI: 1.23–3.14).
  • Smoking status was also associated with favourability toward meetings among users (OR = 1.77; 95% CI: 1.24–2.54).
  • Student interest in formal guidance was described as 'strong,' underscoring the need for universities to integrate evidence-based nutritional and supplement-safety education.

What This Means

This research surveyed over 2,000 university students in Catania, Italy, and found that more than half (55.7%) had used dietary supplements at some point in their lives. Students who felt they were well-informed about supplements were far more likely to use them — about four to five times more likely than those who felt uninformed. However, despite this high self-confidence about supplement knowledge, more than one in three supplement users (34.6%) reported experiencing at least one negative symptom they linked to their supplement use. This suggests that feeling knowledgeable does not necessarily translate into safe supplementation practices. The study also found that where students got their supplement information mattered. Those who received information from health professionals or from friends were both more likely to use supplements, indicating that peer influence plays a nearly as large a role as professional guidance. Students in scientific degree programs were also more likely to use supplements than those in non-scientific fields. Importantly, about three-quarters of all students said they would welcome formal educational sessions from their university on the topic, and daily supplement users were the most enthusiastic about receiving this guidance. This research suggests that universities may have an important opportunity — and a receptive audience — to provide evidence-based education on dietary supplement safety. The gap between students' high confidence in their own knowledge and the relatively high rate of reported side effects points to a need for more structured, institutionally-led information rather than relying on peer networks or self-assessment alone. Integrating supplement and nutrition safety content into university curricula could help students make more informed and safer choices.

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Citation

Leonforte F, Nicosia V, Mercogliano M, Cavallaro A, Morlino G, Chimienti M, et al.. (2026). Prevalence and Correlates of Dietary Supplement Use Among Italian University Students: A Cross-Sectional Study.. Nutrients. https://doi.org/10.3390/nu18172760