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Prevalence and Risk Factors of Various Gastrointestinal Malignancies.

TL;DR

Survival rate in patients with gastrointestinal malignancies is significantly associated with factors such as age, family history, tumor location (colon and pancreas), history of smoking, concomitant disease, metastasis (rectal cancer), and physical activity.

Key Findings

The average age of death among patients with gastrointestinal malignancies was 66.05 years.

  • Data were collected from patients admitted to Baqaei Hospital during 2019 to 2022.
  • Age was identified as a significant factor associated with survival rate in GI malignancy patients.
  • Both linear regression and unadjusted logistic regression analyses were conducted alongside t-test and chi-square methods.

Approximately 20.4% of patients with gastrointestinal malignancies had a family history of cancer.

  • Family history was identified as a significant factor associated with survival rate.
  • Data were gathered via questionnaire including demographic data, occupation, genetic history, and other clinical variables.
  • The study population was drawn from patients admitted to Baqaei Hospital between 2019 and 2022.

Half of the gastrointestinal malignancy patients exhibited metastasis, with rectal cancer having the highest percentage of metastasis among both living and deceased patients.

  • 50% of patients exhibited metastasis overall.
  • Rectal cancer had the highest percentage of metastasis among living and deceased patients.
  • Metastasis in rectal cancer was identified as a significant factor associated with survival rate.

44.8% of patients with gastrointestinal malignancies had a history of smoking, which was significantly associated with survival.

  • Smoking history was one of several factors significantly associated with survival rate in GI malignancy patients.
  • Smoking habits were collected as part of the questionnaire administered to admitted patients.
  • The study period spanned 2019 to 2022 at Baqaei Hospital.

74.8% of patients had underlying diseases, which was significantly associated with survival outcomes.

  • Underlying diseases assessed included hypertension, diabetes, and rheumatism.
  • Concomitant disease was identified as a significant factor associated with survival rate.
  • Data on underlying diseases were collected via structured questionnaire.

Physical inactivity was nearly universal among patients, with 99.6% reporting no exercise, and physical activity was significantly lower in deceased patients.

  • 99.6% of patients had not exercised.
  • Physical activity was significantly lower in deceased patients compared to survivors.
  • Fewer deaths occurred among those with high physical activity levels.
  • Physical activity was identified as a significant factor associated with survival rate in GI malignancy patients.

Tumor location, specifically colon and pancreas, was significantly associated with survival rate in gastrointestinal malignancy patients.

  • Location of malignancy was collected as part of the questionnaire data.
  • Colon and pancreas tumor locations were singled out as significant among the various GI malignancy sites examined.
  • The analysis methods included linear regression, unadjusted logistic regression, t-test, and chi-square statistical methods.

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Citation

Akram A, Roya S, Fereashteh N, Mohamad H, Saeid B, Vahid R. (2026). Prevalence and Risk Factors of Various Gastrointestinal Malignancies.. Archives of Razi Institute. https://doi.org/10.32592/ARI.2025.80.3.719