Re: "Ageism and the feminization of old age: A systematic review".

Older women show higher risk of depression compared to older men.

• This finding is presented as a clinical observation reinforcing review-based policy implications.
• The finding is discussed in the context of gendered late-life vulnerabilities reflecting cumulative life-course disadvantage.
• This is a Letter to the Editor responding to a systematic review on ageism and the feminization of old age.

Older men show higher risk of suicide compared to older women.

• This finding is presented alongside the observation of higher depression risk in older women.
• The authors note distinct mental health pathways for women and men.
• This is framed as a clinical observation that reinforces review-based policy implications.

Social isolation shows distinct mental health pathways for women and men in older age.

• Social isolation is identified as a key factor with gendered differences in mental health outcomes.
• The differential pathways are discussed in the context of cumulative life-course disadvantage.
• This observation is presented as complementary to findings from the original systematic review on ageism and feminization of old age.

Gendered late-life vulnerabilities reflect cumulative life-course disadvantage.

• The authors frame late-life gender disparities as the result of accumulated disadvantages across the life course.
• This perspective is offered as a commentary on a systematic review addressing ageism and the feminization of old age.
• Clinical observations are noted to reinforce review-based policy implications.