Cardiovascular

Repair of Asymmetric Bicuspid Aortic Valve Using Tricuspidation with CardioCel.

TL;DR

A novel tricuspidation technique for asymmetric bicuspid aortic valve repair using CardioCel bovine pericardium neo-cusps resulted in all 15 patients alive with well-functioning valves presenting no or trivial insufficiency, large orifice areas, and nearly physiological transvalvular gradients.

Key Findings

A novel tricuspidation technique was developed for repair of asymmetric bicuspid aortic valves with commissural orientation of approximately 120-140 degrees.

  • The technique involves replacement of the fused aortic valve cusp with 2 neo-cusps
  • Neo-cusps are fashioned from bovine pericardium (CardioCel) and sutured to the annulus
  • The technique is specifically designed for 'very asymmetrical bicuspid aortic valve' with commissural orientation of 'about 120-140 degrees'
  • Successful repair requires 'good quality and adequate commissure height of the non-fused cusp'

The tricuspidation technique was applied to 15 patients since 2020 with all patients surviving and maintaining well-functioning aortic valves.

  • The technique has been applied to 15 patients since 2020
  • To date, all patients are alive
  • All patients presented with 'no or trivial insufficiency'
  • Patients demonstrated 'large orifice areas, and nearly physiological transvalvular gradients'

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Citation

Urbanski P, Irimie V. (2026). Repair of Asymmetric Bicuspid Aortic Valve Using Tricuspidation with CardioCel.. Interdisciplinary cardiovascular and thoracic surgery. https://doi.org/10.1093/icvts/ivag044