Sleep

Risk Factors for Comorbid Anxiety in Patients with Coronary Heart Disease and Association with Noise Exposure.

TL;DR

Patients with CHD are prone to anxiety, with hospital noise being a potential risk factor, and noise reduction management can effectively alleviate anxiety.

Key Findings

CHD patients with comorbid anxiety had significantly higher Self-Rating Anxiety Scale (SAS) scores than those without anxiety.

  • The anxiety group (n=78) had a mean SAS score of 55.64 ± 3.85.
  • The nonanxiety group (n=60) had a mean SAS score of 47.25 ± 2.47.
  • The difference was statistically significant (t = 14.706, P < 0.05).
  • Participants were drawn from 138 CHD patients hospitalized between June 2023 and December 2024.

Noise exposure was positively correlated with anxiety in CHD patients.

  • Pearson correlation analysis yielded r = 0.522, P < 0.05.
  • The anxiety group had significantly higher hospital noise levels (dB) compared to the nonanxiety group (P < 0.05).
  • Elevated noise exposure was identified as an independent determinant of anxiety with an odds ratio of 1.329.

Poor sleep quality, multivessel disease, elevated noise exposure, and prior PCI history were identified as risk factors for comorbid anxiety in CHD patients.

  • Univariate logistic regression identified four significant determinants of anxiety (all P < 0.05).
  • Odds ratios were: poor sleep quality (OR = 7.352), multivessel disease ≥3 vessels (OR = 2.240), elevated noise exposure (OR = 1.329), and prior percutaneous coronary intervention (PCI) history (OR = 2.266).
  • Sleep quality was assessed using the Pittsburgh Sleep Quality Index (PSQI); the anxiety group had significantly higher PSQI scores than the nonanxiety group (P < 0.05).
  • The anxiety group also had higher rates of multivessel disease (≥3 vessels) and prior PCI history compared to the nonanxiety group (both P < 0.05).

Noise reduction management interventions resulted in reduced noise levels and lower SAS anxiety scores compared to baseline.

  • Post-management data showed statistically significant reductions in both noise levels and SAS scores compared to baseline (all P < 0.05).
  • The intervention was implemented during the hospitalization period studied (June 2023 to December 2024).
  • The study design was retrospective, based on clinical data from 138 hospitalized CHD patients.

The study used a retrospective design stratifying 138 hospitalized CHD patients into anxiety and nonanxiety groups based on clinically significant anxiety during hospitalization.

  • Total sample: 138 CHD patients hospitalized between June 2023 and December 2024.
  • Anxiety group: n = 78; nonanxiety group: n = 60.
  • Assessments included noise levels in dB, Pittsburgh Sleep Quality Index (PSQI), Self-Rating Anxiety Scale (SAS), and disease-related parameters.
  • Between-group comparisons, Pearson correlation analysis, and univariate logistic regression were performed.

What This Means

This research suggests that among patients hospitalized with coronary heart disease (CHD), a substantial proportion develop anxiety, and the level of noise in the hospital environment may play a meaningful role. In a study of 138 CHD patients, those with anxiety had notably higher noise exposure, worse sleep quality, more extensive heart disease (three or more blocked blood vessels), and a higher likelihood of having previously undergone a heart procedure called percutaneous coronary intervention (PCI). The strongest individual risk factor for anxiety was poor sleep quality, followed by prior PCI history, multivessel disease, and noise level. The study also found that simply implementing noise reduction strategies in the hospital setting was associated with measurable decreases in both actual noise levels and patient-reported anxiety scores. This suggests that managing the hospital soundscape may be a practical, low-cost way to help reduce psychological distress in this vulnerable patient population. This research suggests that healthcare providers caring for CHD patients should pay close attention to emotional well-being, particularly in patients with multiple risk factors such as complex disease, prior procedures, and poor sleep. Efforts to reduce unnecessary hospital noise—such as quieting alarms, lowering staff conversation volume, and minimizing nighttime disturbances—may offer benefits beyond comfort, potentially improving psychological outcomes for heart disease patients.

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Citation

Chen H, Wang Q. (2026). Risk Factors for Comorbid Anxiety in Patients with Coronary Heart Disease and Association with Noise Exposure.. Noise &amp; health. https://doi.org/10.4103/nah.nah_135_25