The novel antimicrobial wound dressing VELVERT demonstrated improved wound healing efficacy and higher antimicrobial activity compared with AQUACEL Ag Foam dressing in the treatment of diabetic foot ulcers.
Complete wound healing was achieved in more patients in the novel dressing group than in the standard dressing group.
The novel dressing group showed nearly double the percentage of total wound area healed compared with the standard dressing group.
The novel dressing demonstrated substantially greater antimicrobial efficacy, reducing infection rates from 80% to 4% over the course of the study.
The study was a prospective, randomised, two-arm open-label trial enrolling patients with stage 2/3 diabetic foot ulcers.
The novel antimicrobial dressing VELVERT compared favorably to AQUACEL Ag Foam across both wound healing and antimicrobial outcome measures.
This research suggests that a newer wound dressing called VELVERT may work better than an established dressing (AQUACEL Ag Foam) for treating diabetic foot ulcers (DFUs). In a randomized study of 100 patients with DFUs in India, researchers found that wounds treated with the novel dressing healed at roughly twice the daily rate (2.16% per day versus 1.13% per day) and that nearly twice as much of the total wound area had healed by the end of the 28-day study period (60.78% versus 31.76%). Additionally, no improvement at all was seen in four patients using the standard dressing, while all patients using the novel dressing showed at least some progress. One of the most notable findings concerned infection control. Diabetic foot ulcers are particularly prone to infection, which can slow or prevent healing. Even though more patients in the novel dressing group started out with detectable infections (80% versus 50%), by the end of the study, far fewer of them still had infections (4% versus 18%). This suggests the novel dressing has strong antimicrobial properties that help clear infections and allow wounds to heal more effectively. This research matters because diabetic foot ulcers are a serious and common complication of diabetes, sometimes leading to amputation if they do not heal properly. Findings like these could help guide clinicians toward more effective dressing choices, though further large-scale and blinded studies would help confirm these results.
Chand G, Singh S, Kumar R, Madhu K. (2026). Safety and efficacy of a novel antimicrobial wound dressing compared with a standard dressing in diabetic foot ulcers.. Journal of wound care. https://doi.org/10.12968/jowc.2024.0190