Cardiovascular

Screen-detected raised blood pressure and gaps in the hypertension care cascade among adults attending a humanitarian medical mission in Ukraine: A cross-sectional study.

TL;DR

Among adults attending a humanitarian medical mission in Ukraine, 65.7% had raised blood pressure on crude estimate, yet only 15.8% of those with raised blood pressure had it controlled, revealing substantial gaps in the hypertension care cascade.

Key Findings

The crude prevalence of raised blood pressure among adults at a humanitarian medical mission in Ukraine was 65.7%.

  • Study included 364 adults (mean age 52.5 years; 63.2% women) seen consecutively at a MacKay Memorial Hospital mission across three Ukrainian sites in April 2026
  • 341 participants had complete outcome data
  • Crude prevalence was 65.7% (95% CI: 60.5–70.5)
  • Raised blood pressure was defined as a single reading ≥140/90 mmHg or a reported previous hypertension diagnosis

After age standardization to the WHO world population, the prevalence of raised blood pressure fell to 54.7%.

  • Age-standardized prevalence was 54.7% (95% CI: 48.1–61.3)
  • Standardization used the World Health Organization world standard population
  • The reduction from crude (65.7%) to standardized (54.7%) estimates reflects the older age distribution of the sample relative to the world standard population

Older age, male sex, and obesity were each independently associated with raised blood pressure.

  • Adjusted prevalence ratios were derived from modified Poisson regression with robust variance
  • Older age: adjusted prevalence ratio (APR) 1.19 per 10 years (95% CI: 1.11–1.27)
  • Male sex: APR 1.26 (95% CI: 1.08–1.47)
  • Obesity: APR 1.24 (95% CI: 1.09–1.42)
  • Prevalence climbed with age and was higher in men

Among those with raised blood pressure in the cardiovascular screening stream, awareness was 74.6%, treatment was 58.8%, and control was only 15.8%.

  • These figures describe the hypertension care cascade within the cardiovascular screening substream of the mission
  • Awareness: 74.6% of those with raised blood pressure knew about their condition
  • Treatment: 58.8% were on treatment
  • Control: only 15.8% had their blood pressure controlled
  • Authors note that 'estimates held across multiple imputation and alternative specifications'

Blood pressure was assessed using a single reading per participant, and the sample was self-selected, limiting generalizability to population-level prevalence.

  • Blood pressure was taken once per participant
  • The study was cross-sectional in design
  • Authors explicitly state the sample 'cannot speak to population prevalence'
  • Participants were adults (≥18 years) seen consecutively at a humanitarian mission, constituting a self-selected sample
  • The study was conducted across three Ukrainian sites in April 2026 during a period of active conflict

The authors argue that the pattern of common raised blood pressure with poor control supports integrating simple screening and a clear referral pathway into humanitarian medical missions.

  • Authors characterize the pattern as 'common raised blood pressure with poor control'
  • They describe this as making 'a reasonable case for building simple screening and a clear referral pathway into missions of this kind'
  • The study context was a conflict setting (Ukraine) where long-term hypertension care is likely disrupted
  • Little prior screening data existed from settings of active conflict, according to the authors

What This Means

This research suggests that among adults who attended a humanitarian medical mission in Ukraine during active conflict, high blood pressure was extremely common and poorly managed. Nearly two-thirds of participants had elevated blood pressure based on a single measurement or a prior diagnosis, and even after adjusting for the age distribution of the sample, more than half still met the criteria. Being older, male, or obese were each independently linked to a higher likelihood of having elevated blood pressure. These findings point to a population under significant cardiovascular stress, consistent with the disruptions to routine medical care that conflict typically causes. Perhaps more striking than the high prevalence was the state of care for those affected. While about three-quarters of people with high blood pressure were aware of their condition, fewer than 60% were receiving treatment, and only about 1 in 6 had their blood pressure under control. This 'care cascade' — from awareness to treatment to control — shows where people are falling through the cracks, with the biggest gap occurring at the control stage. The pattern suggests that even among people who know they have high blood pressure and are taking medication, effective management is rare in this setting. This research suggests that integrating basic blood pressure screening and clear referral pathways into humanitarian medical missions could have meaningful public health value. The authors are careful to note that because participants self-selected to attend the mission and blood pressure was only measured once, the findings cannot be taken as representative of the broader Ukrainian population. Nevertheless, the consistent pattern of high prevalence and low control provides a practical rationale for making hypertension screening a routine component of humanitarian medical operations in conflict zones.

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Citation

Chen K, Yen E, Tsai K, Lin S, Maistrova R, Tsai W. (2026). Screen-detected raised blood pressure and gaps in the hypertension care cascade among adults attending a humanitarian medical mission in Ukraine: A cross-sectional study.. PloS one. https://doi.org/10.1371/journal.pone.0357957