Cardiovascular

Severity and distribution of coronary artery disease in lebanese patients undergoing coronary angiography: Impact of gender and age on angiographic characteristics, a cross-sectional study.

TL;DR

Gender and age are associated with distinct angiographic patterns of CAD, with male gender linked to more extensive coronary disease and older age associated with greater comorbidity burden and impaired ventricular function in Lebanese patients.

Key Findings

The study included 212 Lebanese patients with angiographically confirmed CAD with a mean age of 60.6 years and slight male predominance.

  • Total sample size was 212 patients with CAD
  • 51.4% of patients were male
  • Mean age was 60.6 years
  • Patients were enrolled between January 2021 and February 2022
  • This was described as the first study in Lebanon to evaluate gender- and age-related differences in angiographic patterns and clinical characteristics of CAD

Male patients more frequently had prior angina, myocardial infarction, and coronary revascularization compared to female patients.

  • Prior history of angina, myocardial infarction, and coronary revascularization were all more common in male patients
  • These differences were observed in a multicenter, cross-sectional study design
  • Data were obtained through patient interviews and comprehensive review of medical records

Male patients exhibited more severe coronary lesions, particularly involving the left anterior descending artery.

  • Males showed more severe coronary lesions compared to females
  • The left anterior descending artery was particularly more involved in male patients
  • Among patients with multivessel disease (MVD), males had a greater extent of coronary involvement

Younger patients (≤55 years) more often reported a family history of CAD compared to older patients.

  • Patients were stratified into younger (≤55 years) and older (>55 years) age groups
  • Family history of CAD was more frequently reported among younger patients
  • This suggests a stronger hereditary component in early-onset CAD in this Lebanese population

Older patients (>55 years) had a higher prevalence of cardiovascular comorbidities, prior ischemic events, coronary interventions, heart failure, and reduced left ventricular ejection fraction.

  • Older patients (>55 years) demonstrated greater comorbidity burden compared to younger patients
  • Prior ischemic events and coronary interventions were more common in the older age group
  • Heart failure and reduced left ventricular ejection fraction were more prevalent in older patients
  • Echocardiographic assessment of left ventricular systolic function was included in data collection

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Citation

Al Chaar S, Al Hajj A, Nakad P, Sarraf A, Halby J, Fakhry B, et al.. (2026). Severity and distribution of coronary artery disease in lebanese patients undergoing coronary angiography: Impact of gender and age on angiographic characteristics, a cross-sectional study.. Medicine. https://doi.org/10.1097/MD.0000000000048086