Sex-Specific Factors Associated With Suicidal Ideation Among Individuals With Type 2 Diabetes: A Cross-Sectional Study.

Being married was significantly associated with increased suicidal ideation in men with type 2 diabetes.

• Adjusted odds ratio (AOR) for marriage in men = 4.54
• Cross-sectional study of 695 adults with T2D at a university hospital outpatient clinic
• 406 (58.4%) of participants were men
• Mean age of sample was 60.5 (SD = 11.8)
• Multiple logistic regression was used to identify sex-specific factors

Living with someone was associated with significantly lower suicidal ideation in men with type 2 diabetes.

• AOR for living with someone in men = 0.16, indicating a protective effect
• This finding suggests that the nature of cohabitation, not just marital status, matters for suicide risk in men
• The authors note the need for 'interpreting the influence of social support by gender'
• Finding highlights a distinction between marital status and actual social cohabitation as risk/protective factors

Elevated creatinine levels were strongly associated with suicidal ideation in women with type 2 diabetes.

• AOR for elevated creatinine in women = 11.69
• 289 (41.6%) of participants were women
• Creatinine data were obtained from electronic health records
• Elevated creatinine may indicate kidney dysfunction, a known complication of type 2 diabetes

Smoking was strongly associated with suicidal ideation in women with type 2 diabetes.

• AOR for smoking in women = 10.84
• Smoking was not identified as a significant factor in men in this study
• This represents a sex-specific psychosocial and behavioral risk factor
• Clinical and behavioral data were obtained from electronic health records and self-reported questionnaires

Higher fatigue was consistently associated with suicidal ideation in both men and women with type 2 diabetes.

• AOR for fatigue in men = 1.44
• AOR for fatigue in women = 1.43
• Fatigue was assessed using self-reported questionnaires
• The authors describe fatigue as 'a consistently associated factor of suicidal ideation' across both sexes
• Authors conclude that 'fatigue management is crucial for the prevention of suicide among individuals with T2D'

The study identified distinct sex-specific profiles of suicidal ideation risk factors among adults with type 2 diabetes.

• In men, key factors were marital status (AOR = 4.54), living arrangement (AOR = 0.16), and fatigue (AOR = 1.44)
• In women, key factors were creatinine (AOR = 11.69), smoking (AOR = 10.84), and fatigue (AOR = 1.43)
• Study was conducted between May 2022 and April 2023 at a university hospital outpatient clinic
• Authors highlight 'the need for tailored suicide risk screening and for interpreting the influence of social support by gender'