Sexual health is substantially affected by haematological malignancies and their treatments, and addressing intimate aspects of patients' lives enhances wellbeing and survivorship quality, yet novel multidisciplinary strategies are needed.
Key Findings
Background
Sexual dysfunction is highly prevalent among patients with haematological malignancies, affecting both male and female patients.
Disease diagnosis, treatment, and follow-up all contribute to negative effects on sexual health
Both the physical and psychological dimensions of sexual health are impacted
Partners, family members, and friends are also affected by these changes
Sexual health issues persist into survivorship, not just during active treatment
Results
Haematological cancer treatments including chemotherapy, radiation, and stem cell transplantation contribute to sexual dysfunction through multiple mechanisms.
Treatments can cause hormonal disruptions, gonadal damage, and fertility impairment
Stem cell transplantation, including allogeneic transplant, is associated with significant sexual health complications
Graft-versus-host disease (GvHD) following transplantation can directly affect sexual organs and function
Physical side effects such as fatigue, pain, and body image changes compound sexual health issues
Results
Psychological and emotional factors significantly contribute to sexual health problems in patients with haematological cancers.
The shock of diagnosis and treatment-related anxiety negatively affect intimacy and sexual function
Depression and emotional distress are commonly associated with reduced sexual wellbeing
Relationship dynamics and partner communication are affected by the cancer experience
Emotional wellbeing and sexual health are closely interlinked throughout the cancer journey
Results
Multiple validated tools and instruments exist to assess sexual function in patients with haematological malignancies, though their use remains inconsistent in clinical practice.
Different methods to assess sexual function are discussed, applicable to both male and female patients
Assessment tools capture both physical and psychological dimensions of sexual health
Standardized assessment is needed to better identify and address sexual health concerns
Many patients and haematologists acknowledge that intimacy and sexuality issues are substantial during treatment, yet these are underaddressed
Results
Management of sexual health complications in haematological cancer patients requires a multidisciplinary approach encompassing pharmacological, psychological, and rehabilitative strategies.
Progress has been made in the management of sexual life-related complications
Novel strategies in coordination with a multidisciplinary team need to be implemented
New and comprehensive approaches must be developed on a multidisciplinary scale
Management approaches discussed include interventions addressing both physical and emotional dimensions of sexual wellbeing
Background
Addressing sexual health in haematological cancer patients contributes to overall quality of life and survivorship quality.
Addressing the intimate aspects of patients' lives 'not only enhances their wellbeing but also contributes to the quality of their survivorship'
Sexual health is described as 'an important aspect of a person's life'
Quality of life implications extend beyond the patient to partners and other family members
Survivorship considerations make sexual health a long-term concern beyond the acute treatment phase
What This Means
This research examines how blood cancers (haematological malignancies) affect the sexual health and emotional wellbeing of patients. The study found that every stage of the cancer experience — from the initial diagnosis and the shock of being told one has cancer, through treatment, and into follow-up care — can negatively affect a person's sexual life and intimate relationships. Treatments such as chemotherapy, radiation, and stem cell transplantation can cause hormonal changes, damage to reproductive organs, and physical side effects like fatigue and altered body image, all of which contribute to sexual difficulties. Psychological factors like depression and anxiety add to these challenges, and the effects extend beyond patients themselves to their partners and families.
The paper highlights that both patients and their haematologists recognize sexual and intimacy issues as significant during cancer treatment, yet these concerns are often not adequately addressed in clinical care. Various tools exist to measure sexual function and wellbeing, but they are not consistently used. This research suggests that a coordinated, multidisciplinary team approach — involving doctors, psychologists, and other healthcare professionals — is needed to properly assess and manage sexual health alongside other aspects of cancer care.
The broader implication is that attending to sexual health is not a peripheral concern but a meaningful part of cancer survivorship and overall quality of life. This research suggests that healthcare systems should develop more comprehensive, team-based strategies to support patients' intimate and emotional wellbeing throughout their cancer journey, recognizing that improvements in this area can enhance patients' overall experience of survivorship.
Alsuliman T, Rojas R, Moukalled N, Brissot E, Quarez-Blaise L, Marjanovic Z, et al.. (2024). Sexual health and emotional wellbeing of patients with haematological malignancies: general review.. The Lancet. Haematology. https://doi.org/10.1016/S2352-3026(24)00208-4