Sexual dysfunction is common among lung cancer patients, with less than half reporting recent sexual activity and many expressing little to no interest or satisfaction, yet it remains an underassessed concern in oncology care.
Key Findings
Results
Less than half of lung cancer patients in treatment reported recent sexual activity.
45.9% of participants reported recent sexual activity
Cross-sectional survey of 61 completed responses from 69 recruited patients
Participants were recruited from 1 July 2023 to 30 September 2024
Eligibility required LC diagnosis, age >18 years, ability to read, and at least 1 month of treatment
Results
The majority of lung cancer patients reported little to no interest in sexual activity.
55.7% expressed little to no interest in sexual activity
42.8% reported minimal satisfaction with their sex life
The sample was predominantly male (67.2%) with stage IV LC (68.9%)
A questionnaire on sexual activity and satisfaction was used as the assessment tool
Results
Fatigue and anxiety/stress were the most commonly reported factors affecting sexual satisfaction.
Fatigue was cited by 37.7% of participants as a factor affecting sexual satisfaction
Feelings of anxiety/stress were cited by 24.6% of participants
These psychophysical factors were identified through the survey questionnaire
Results
Lack of interest, erectile difficulties, and partner-related issues were the primary reasons reported for decreased sexual activity.
Lack of interest was cited by 36.4% of participants as a reason for decreased sexual activity
Difficulties with erection were reported by 24.2% of participants
Issues with partners were reported by 24.3% of participants
Results
A significant association was found between sexual dysfunction scores and the perceived impact of lung cancer on sexual life.
Higher dysfunction scores were linked to more negative reports of LC's impact on sexual life
The association was described as statistically significant
Sexual dysfunction prevalence in LC patients is described as 'largely unknown' prior to this study
The study used a cross-sectional design, which limits causal inference
Methods
The study sample was predominantly composed of male patients with advanced-stage lung cancer.
67.2% of participants were male
68.9% had stage IV lung cancer
61 patients completed the survey out of 69 recruited
The study was conducted at a single center
What This Means
This research suggests that sexual dysfunction is a common but underrecognized problem among people being treated for lung cancer. In a survey of 61 lung cancer patients, fewer than half reported any recent sexual activity, and more than half had little to no interest in sex. Many also reported low satisfaction with their sex lives. The most common reasons patients gave for these difficulties included fatigue, anxiety and stress, lack of interest, problems with erections, and issues within their relationships with partners.
The study also found that patients who scored higher on measures of sexual dysfunction were more likely to feel that lung cancer had negatively affected their sexual lives. This suggests the two are closely connected — that the disease and its treatment take a meaningful toll on this aspect of patients' wellbeing. Most participants had advanced (stage IV) lung cancer, meaning these findings are particularly relevant to people managing a serious, ongoing illness.
This research suggests that sexual health concerns are not being adequately addressed in lung cancer care, even though they affect a substantial proportion of patients. The authors conclude that oncology teams should implement routine assessment of sexual health and offer appropriate interventions, as doing so could meaningfully improve patients' quality of life during and after treatment.
Costa M, Fernandes C, Leite J, Vilaça M, Estevinho F, Magalhães H. (2025). Sexual Health of Patients in Treatment for Lung Cancer: An Undercover Concern for Patients and Oncologists.. Current oncology (Toronto, Ont.). https://doi.org/10.3390/curroncol32020107