Sleep

Short sleep duration and incident self-reported severe periodontitis among Japanese adults: a nationwide prospective cohort study.

TL;DR

Short sleep duration (<6 hours per night) was associated with a higher risk of self-reported incident severe periodontitis (hazard ratio = 1.28, 95% CI: 1.13–1.46) in a nationwide prospective cohort of Japanese adults.

Key Findings

Short sleep duration was associated with a significantly higher risk of self-reported incident severe periodontitis in the primary analysis.

  • Hazard ratio = 1.28, 95% confidence interval: 1.13–1.46
  • Short sleep duration was defined as less than 6 hours per night
  • Cox proportional hazards models were used as the primary analysis
  • 22.7% of participants reported short sleep duration at baseline

The association between short sleep duration and incident severe periodontitis was consistent in a secondary analysis using repeated measures.

  • Odds ratio = 1.26, 95% CI: 1.09–1.46 in the secondary analysis
  • Generalized estimating equations were used for the secondary analysis with repeated measures
  • The consistency across two analytic approaches supports the robustness of the finding

The study population consisted of 8,144 Japanese adults without self-reported severe periodontitis at baseline who had follow-up data.

  • Participants were drawn from 33,000 respondents to the 2023 wave of the Japan COVID-19 and Society Internet Survey
  • The study used longitudinal data from the 2023–2025 waves of the survey
  • Participants were followed for self-reported incident severe periodontitis over the study period
  • This was a nationwide prospective cohort design

Older age, lower income, diabetes, dyslipidaemia, depression, and smoking were also associated with an increased risk of incident severe periodontitis.

  • These factors were identified alongside short sleep duration as risk factors in the Cox proportional hazards models
  • These findings are consistent with known behavioral, systemic, and socioeconomic influences on periodontitis
  • The paper notes that periodontitis is a chronic inflammatory condition influenced by behavioral, systemic, and socioeconomic factors

The authors conclude that short sleep duration may be a modifiable risk factor for severe periodontitis in the general population.

  • Prior evidence on this association was largely from cross-sectional studies, leaving longitudinal evidence limited
  • The authors highlight 'the potential importance of sleep for the prevention of periodontitis'
  • The modifiable nature of sleep duration is noted as clinically relevant for prevention

What This Means

This research suggests that people who sleep fewer than 6 hours per night are about 28% more likely to develop severe gum disease (periodontitis) compared to those who sleep longer. The study followed over 8,000 Japanese adults who did not have severe periodontitis at the start, tracking them over two years through a large national internet survey. Both the main statistical analysis and a confirmatory follow-up analysis produced similar results, strengthening confidence in the finding. The study also found that other factors — including older age, lower income, diabetes, high cholesterol (dyslipidaemia), depression, and smoking — were linked to a greater risk of developing severe periodontitis, which is consistent with what scientists already know about gum disease. Importantly, about 1 in 4 participants in this study reported sleeping less than 6 hours per night, suggesting that short sleep is a common and potentially impactful risk factor in the general population. This research suggests that sleep may play a meaningful role in oral health, possibly because poor sleep can weaken the immune system and increase inflammation throughout the body, which could make the gums more vulnerable to disease. Since sleep duration is something that can potentially be improved, these findings point to sleep as a possible target for efforts to prevent gum disease — alongside more established factors like not smoking and managing chronic health conditions. However, because participants self-reported both their sleep and their gum disease, and the study was conducted in Japan using an internet survey, further research in different populations and with clinical measurements would help confirm these findings.

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Citation

Takeuchi N, Itoi K, Maruyama T, Tabuchi T, Ekuni D. (2026). Short sleep duration and incident self-reported severe periodontitis among Japanese adults: a nationwide prospective cohort study.. Frontiers in public health. https://doi.org/10.3389/fpubh.2026.1946230