Sleep

Sleep and Quality of Life Before and After Surgery in Patients With Low-Grade Lumbar Spondylolisthesis.

TL;DR

Surgery for low-grade lumbar spondylolisthesis yields substantial benefits, extending beyond pain control to improvements in sleep quality, functional capacity, and overall quality of life.

Key Findings

Visual Analog Scale pain scores decreased significantly following posterior decompression and instrumented fusion surgery for low-grade lumbar spondylolisthesis.

  • 55 patients were included in this prospective observational study
  • VAS scores were measured preoperatively and on the 90th postoperative day
  • The decrease in VAS scores was statistically significant (P<0.001)
  • The improvement indicated 'effective pain relief' per the authors

Pittsburgh Sleep Quality Index scores decreased markedly after surgery, indicating improved sleep quality in patients with low-grade lumbar spondylolisthesis.

  • PSQI was administered preoperatively and at 90 days postoperatively
  • The improvement in PSQI scores was statistically significant (P<0.001)
  • This was a prospective observational study with 55 patients
  • Authors noted evidence on sleep quality in homogeneous cohorts of spondylolisthesis patients was previously scarce

Oswestry Disability Index scores decreased significantly after surgery, reflecting improved functional capacity.

  • ODI was assessed preoperatively and on postoperative day 90
  • Reduction in ODI scores was statistically significant (P<0.001)
  • All 55 patients who underwent posterior decompression and instrumented fusion were evaluated
  • Authors described this as indicating 'improved functional capacity'

EuroQol-5 Dimensions-3 Levels scores increased significantly after surgery, reflecting enhanced overall quality of life.

  • EQ-5D-3L scores were measured preoperatively and at 90 days postoperatively
  • The increase in EQ-5D-3L scores was statistically significant (P<0.001)
  • The improvement was described as 'reflecting enhanced overall quality of life'
  • Sample size was 55 patients undergoing posterior decompression and instrumented fusion

Subgroup analyses demonstrated consistent postoperative benefits across spondylolisthesis types and grades, with male patients exhibiting greater improvements in quality-of-life measures.

  • Subgroup analyses were performed by spondylolisthesis type and grade
  • Benefits were described as 'consistent' across subgroups
  • Male patients showed greater improvements specifically in quality-of-life measures compared to female patients
  • The study population included patients with low-grade lumbar spondylolisthesis (implying Grades I and II)

All evaluated outcome parameters showed significant postoperative improvements at 90 days following surgery for low-grade lumbar spondylolisthesis.

  • Four instruments were used: VAS, PSQI, EQ-5D-3L, and ODI
  • All instruments showed statistically significant improvement (all P<0.001)
  • Assessments were conducted preoperatively and on the 90th postoperative day
  • The study was a prospective observational design with 55 patients
  • Surgical procedure was posterior decompression and instrumented fusion

What This Means

This research suggests that surgery for a spine condition called low-grade lumbar spondylolisthesis — where one vertebra slips forward over another — provides meaningful benefits that go well beyond simply reducing pain. In a study of 55 patients who underwent a specific spinal surgery (posterior decompression and instrumented fusion), researchers measured pain levels, sleep quality, physical function, and overall quality of life before the operation and again 90 days afterward. All four measures improved significantly after surgery, suggesting that this type of operation can substantially improve patients' day-to-day lives within three months. Notably, the study found that sleep quality improved significantly after surgery, which is an outcome that has not been well-studied in this specific patient population before. Pain relief, better ability to perform daily activities, and improved general well-being were also documented. When the researchers looked at subgroups, the benefits were consistent regardless of the specific type or grade of spondylolisthesis, though male patients appeared to experience greater gains in quality-of-life scores than female patients. This research suggests that for patients with low-grade lumbar spondylolisthesis who have not responded to non-surgical treatments, surgery may be a reliable option that addresses not just physical symptoms like pain but also broader aspects of wellbeing including sleep and psychosocial health. The findings highlight the importance of considering sleep and quality of life — not just pain — when evaluating the success of spinal surgery.

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Citation

Tun&#xe7; B, Uzlu O, &#x15e;ahin &, &#xdc;nal E, Y&#x131;lmaz A, &#xc7;a&#x11f;&#x131;l E. (2026). Sleep and Quality of Life Before and After Surgery in Patients With Low-Grade Lumbar Spondylolisthesis.. Medical science monitor : international medical journal of experimental and clinical research. https://doi.org/10.12659/MSM.950921