[Sleep disorders dynamics in patients with chronic thromboembolic pulmonary hypertension after surgical treatment].

Sleep apnea/hypopnea and nocturnal hypoxemia remained highly prevalent in CTEPH patients after surgical treatment despite significant hemodynamic improvements.

• After surgical treatment, 83.8% of patients maintained sleep apnea/hypopnea.
• Nocturnal hypoxemia persisted in 74.4% of patients after surgical treatment.
• Mean pulmonary artery pressure (mPAP) significantly decreased after treatment (p < 0.0001).
• Pulmonary vascular resistance (PVR) significantly decreased after treatment (p < 0.0001).

Baseline percentage of total sleep time with oxygen saturation below 90% (T90) was significantly associated with postoperative hemodynamic and functional outcomes.

• Baseline T90 was significantly associated with postoperative mPAP (p = 0.0289).
• Baseline T90 was significantly associated with postoperative PVR (p = 0.0050).
• Baseline T90 was significantly associated with postoperative six-minute walk test distance (6MWD) (p = 0.0305).
• The study included 43 patients with verified CTEPH diagnosis hospitalized between December 2023 and February 2025.

A preoperative T90 greater than 11.0% demonstrated 85.7% sensitivity in predicting achievement of the target six-minute walk distance after treatment.

• The T90 threshold of >11.0% before intervention showed 85.7% sensitivity for predicting target 6MWD achievement.
• This predictive association was statistically significant (p = 0.0130).
• Assessment was performed before treatment and at least 3 months after completing balloon pulmonary angioplasty or pulmonary thromboendarterectomy.
• Sleep monitoring used polyfunctional sleep monitoring alongside standardized questionnaires including STOP-Bang, Epworth Sleepiness Scale, Pittsburgh Sleep Quality Index, Insomnia Severity Index, and the International Restless Legs Syndrome Study Group Rating Scale.