Sleep

Sleep Health in Critically Ill Children With Acute Respiratory Failure.

TL;DR

Critically ill children demonstrated disrupted sleep health, with irregular PICU sleep behaviors, frequent sedation, little daytime activity consolidation, and short fragmented sleep episodes that rarely matched baseline sleep patterns.

Key Findings

A substantial proportion of critically ill children had atypical baseline sleep health prior to PICU admission.

  • 52 participants aged 6 months to 17 years were included in the secondary analysis of the RESTORE Resilience (R2) trial.
  • 49 of 52 participants provided prehospital sleep data.
  • 22 of 49 participants (45%) had atypical baseline sleep health.
  • Baseline sleep health was assessed via parent report.

Children in the PICU spent a significant portion of their time sedated.

  • Participants spent greater than or equal to 25% of PICU days in a sedated state.
  • This was measured using alertness levels as part of PICU sleep health assessment.
  • Sedation represents a major confound for sleep health assessment and intervention in the PICU setting.

Total sleep time in the PICU rarely matched participants' baseline sleep duration.

  • Total sleep time was within 1 hour of baseline on only 23 study days, representing 11% of study days.
  • Sleep timing, efficiency, and duration were measured using actigraphy.
  • This finding indicates that PICU sleep is substantially divergent from children's normal sleep patterns.

Critically ill children demonstrated little daytime activity consolidation and experienced short, fragmented sleep episodes in the PICU.

  • Actigraphy-based measures captured sleep timing, efficiency, and duration.
  • Children showed irregular PICU sleep behaviors overall.
  • Short and fragmented sleep episodes were observed across the sample.
  • Little daytime activity consolidation suggests disrupted circadian rhythmicity.

There were few associations between baseline sleep health and PICU sleep health.

  • Analyses compared parent-reported baseline sleep health with PICU sleep health measures.
  • Few statistically significant associations were found between prehospital and in-hospital sleep measures.
  • This suggests PICU environment factors may override individual baseline sleep patterns.

Implementation of the nurse-led chronotherapeutic care bundle (R2 bundle) showed few associations with PICU sleep health outcomes.

  • The R2 bundle was a nurse-led chronotherapeutic care intervention tested in the RESTORE Resilience trial.
  • Few associations were found between R2 bundle implementation and PICU sleep health measures.
  • This secondary analysis included 52 R2 trial participants receiving usual care or the nurse-led bundle.
  • Results will inform future nurse-led interventions to promote sleep in the PICU.

Nearly half of critically ill children with acute respiratory failure had atypical sleep health even before their PICU admission.

  • 45% (22/49) of children who provided prehospital data had atypical baseline sleep health.
  • The sample included children aged 6 months to 17 years with acute respiratory failure.
  • Parent-reported data was used to characterize baseline sleep health.
  • This finding highlights that pre-existing sleep problems are common in this population.

What This Means

This research suggests that children admitted to the pediatric intensive care unit (PICU) with serious breathing problems experience severely disrupted sleep. The study looked at 52 children between 6 months and 17 years old and found that their sleep in the hospital almost never matched their normal sleep patterns from home — in fact, their total sleep time was within one hour of their usual amount on only 11% of hospital days. Children also spent at least a quarter of their hospital days heavily sedated, had very little normal daytime activity, and their sleep came in short, broken-up episodes rather than consolidated rest. Notably, nearly half of the children (45%) already had unusual or problematic sleep patterns before they were even hospitalized, suggesting pre-existing sleep challenges in this population. The study also tested whether a special nursing care program designed to support healthy sleep timing (the 'chronotherapeutic care bundle') made a difference, but found little evidence that it significantly changed children's sleep patterns in the PICU. This may reflect how difficult it is to improve sleep in an environment filled with medical equipment, frequent check-ins, bright lights, and the use of sedating medications. This research matters because poor sleep in children can interfere with healing, brain development, and recovery from illness. By carefully documenting just how disrupted sleep is in critically ill children — and that many already had sleep problems before admission — this study provides a foundation for developing better, more targeted nursing strategies to improve sleep for children in intensive care settings.

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Citation

Kalvas L, Dawkins-Henry O, Ordway M, Kudchadkar S, Asaro L, Wypij D, et al.. (2026). Sleep Health in Critically Ill Children With Acute Respiratory Failure.. AACN advanced critical care. https://doi.org/10.4037/aacnacc2026606