Sleep

Sleep Quality in Adults with Cancer: Associations with Symptom Burden and Psychological Resilience.

TL;DR

Poor sleep was common among adults with cancer, and mental health and resilience were independently associated with sleep quality beyond clinical characteristics, highlighting the relevance of considering psychosocial factors alongside clinical characteristics when assessing sleep problems in supportive oncology care.

Key Findings

Poor sleep quality was highly prevalent among adults with cancer in this sample.

  • The mean sleep quality score was 6.99 ± 3.84 on the Pittsburgh Sleep Quality Index (PSQI)
  • 42.1% of participants were classified as poor sleepers
  • The study included 159 adults with cancer recruited from a tertiary hospital and online patient communities in the Republic of Korea
  • Sleep quality was assessed using the Pittsburgh Sleep Quality Index

Being 1-3 years post-diagnosis was independently associated with higher odds of poor sleep quality.

  • This association was identified through multivariable logistic regression
  • The finding was independent of other sociodemographic and clinical factors
  • The cross-sectional design precluded causal interpretation

Having received radiotherapy was independently associated with higher odds of poor sleep quality.

  • Radiotherapy was identified as an independent clinical factor associated with poor sleep in multivariable logistic regression
  • The association was independent of sociodemographic and other clinical characteristics
  • Treatment type was among the clinical variables examined in the regression models

Higher mental health summary scores were associated with lower odds of poor sleep quality after adjustment for sociodemographic and clinical factors.

  • Mental health was measured using the Patient-Reported Outcomes Measurement Information System 29-Item Profile (PROMIS-29)
  • The association was identified in multivariable logistic regression after adjustment for sociodemographic and clinical factors
  • Symptom burden was assessed across multiple physical and psychological domains using the PROMIS-29

Higher resilience was independently associated with lower odds of poor sleep quality after adjustment for sociodemographic and clinical factors.

  • Resilience was measured with the Korean version of the Connor-Davidson Resilience Scale
  • The association remained significant after adjustment for sociodemographic and clinical factors in multivariable logistic regression
  • Resilience was associated with sleep quality independently of mental health summary scores and clinical characteristics

The final hierarchical regression model explained 34.1% of the variance in sleep quality scores.

  • Hierarchical multiple linear regression was used to examine factors associated with sleep quality scores
  • The final model explained 34.1% of the variance in sleep quality
  • The model incorporated sociodemographic, clinical, symptom burden, and resilience variables in hierarchical steps

What This Means

This research suggests that sleep problems are very common among Korean adults living with cancer, with more than four in ten study participants classified as poor sleepers. The study examined 159 cancer patients and found that certain clinical factors — specifically being 1 to 3 years past their cancer diagnosis and having received radiation therapy — were linked to a higher likelihood of poor sleep. Importantly, the researchers also found that better mental health and greater personal resilience were each independently linked to better sleep quality, even after accounting for medical and demographic characteristics. The study is notable because it looked at both the physical symptom burden and psychological factors together, rather than examining them separately. The finding that resilience — a person's ability to bounce back from adversity — was associated with better sleep quality alongside mental health status suggests that psychological strengths matter for sleep outcomes in cancer patients, not just the medical aspects of their illness or treatment. This research suggests that healthcare providers caring for cancer patients should consider psychosocial factors like mental health status and resilience when evaluating and addressing sleep problems, rather than focusing solely on clinical or disease-related characteristics. Supportive oncology care that addresses psychological wellbeing and builds resilience may be relevant to improving sleep quality in this population.

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Citation

Park R, Lee S. (2026). Sleep Quality in Adults with Cancer: Associations with Symptom Burden and Psychological Resilience.. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer. https://doi.org/10.1007/s00520-026-11353-y