Cardiovascular

Successful single-center experiences of laser crossectomy in zone zero in Endovenous Laser Ablation (EVLA) for chronic venous insufficiency - a case series.

TL;DR

Zone-zero laser crossectomy using a 1470 nm radial double-ring swift laser demonstrated complete GSV obliteration with no recanalization at 3-month follow-up and low complication rates in 57 consecutive patients with chronic venous insufficiency.

Key Findings

Zone-zero laser crossectomy achieved complete obliteration of treated great saphenous veins with no recanalization observed during the 3-month follow-up period.

  • Duplex ultrasound confirmed complete obliteration of all treated GSVs
  • Follow-up was conducted at 7 days, 4, 8, and 12 weeks with physical and duplex ultrasound examinations
  • 57 consecutive patients were included in the case series
  • No recanalization was observed at any follow-up time point through 3 months

The overall postoperative complication rate was low, with all complications being mild and managed conservatively.

  • Leg pain occurred in 3 cases (5.26%)
  • EHIT (Endovenous Heat-Induced Thrombus) grade I-II occurred in 1 case (1.75%)
  • Hyperpigmentation occurred in 1 case (1.75%)
  • Paresthesia occurred in 1 case (1.75%)
  • All complications were described as mild and managed conservatively

The study population consisted of 57 consecutive patients with symptomatic GSV insufficiency spanning CEAP clinical classes C2 through C6.

  • Mean patient age was 61.6 years
  • All patients had symptomatic GSV insufficiency classified as CEAP C2-C6
  • All patients underwent EVLA using a 1470 nm radial double-ring swift laser
  • Zone-zero ablation was performed exactly at the 0 cm zone of the saphenofemoral junction (SFJ)

Zone-zero laser crossectomy is defined as laser ablation performed exactly at the 0 cm zone of the saphenofemoral junction, as a modification of conventional EVLA.

  • Conventional EVLA is typically performed 1-2 cm distal to the saphenofemoral junction (SFJ)
  • Conventional technique was noted to often leave residual tributaries, increasing the risk of recurrence
  • Zone-zero ablation was proposed as a minimally invasive alternative to eliminate residual stumps and reduce varicose vein recurrence
  • The technique used a 1470 nm radial double-ring swift laser

Chronic venous insufficiency is described as a prevalent and underdiagnosed disease with a substantial global burden.

  • CVI affects over 25 million adults worldwide
  • EVLA is described as the gold standard for great saphenous vein insufficiency
  • GSV insufficiency treated with conventional EVLA carries risk of recurrence due to residual tributaries at the SFJ stump

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Citation

Taofan T, Ardiarto S, Indriani S, Aurora R, Dhivi A, Munandar A, et al.. (2026). Successful single-center experiences of laser crossectomy in zone zero in Endovenous Laser Ablation (EVLA) for chronic venous insufficiency - a case series.. F1000Research. https://doi.org/10.12688/f1000research.170645.1