Cardiovascular

Temporal Assessment of Pressure and Stiffness in Compression Therapy for Venous Leg Ulcers: Implications for Clinical Optimization.

TL;DR

Initial sub-bandage pressures in compression therapy for venous leg ulcers were higher than guideline recommendations but showed notable reduction within the first 24 hours, stabilising within therapeutic ranges for the remainder of the 96-hour study period.

Key Findings

Initial sub-bandage pressures exceeded guideline recommendations but stabilised within therapeutic ranges after the first 24 hours.

  • Pressures were measured over a 96-hour period at three anatomical points in the leg
  • A notable reduction in pressure occurred within the first 24 hours
  • Pressures stabilised within therapeutic ranges for the remainder of the 96-hour study period
  • The authors attribute the initial high pressures to material settlement or application technique compensating for expected loss

Most compression systems demonstrated low dynamic and static stiffness.

  • Both dynamic and static stiffness were assessed across the compression systems studied
  • The majority of systems evaluated showed low values for both stiffness measures
  • Stiffness was measured under different positions and activities
  • This finding has implications for the classification and clinical selection of compression systems

No significant differences in sub-bandage pressure were attributable to the nurses applying the bandages.

  • Bandage application technique was standardised through specific training provided to advanced practice nurses
  • The study included a multicentre design across Andalusia
  • No significant pressure differences were found based on which healthcare professional applied the bandage
  • Standardised training may have contributed to the consistency observed across practitioners

No significant pressure differences were found based on the location of the venous leg ulcer injury.

  • Sub-bandage pressures were measured at three anatomical points in the leg
  • Measurements were taken under different positions and activities
  • Ulcer location did not significantly influence the pressure readings obtained
  • The study included 140 patients with active venous leg ulcers (VLUs) in Andalusia

The study assessed the relationship between sub-bandage pressure and healing outcomes in venous leg ulcer patients.

  • This was a prospective observational multicentre study including 140 patients with active VLUs
  • Patients were drawn from the Andalusian Health System (SAS)
  • The study monitored pressure dynamics over 96 hours
  • Analysing the influence of pressure on healing was listed as an additional objective of the study

Sustained pressure stability over 96 hours confirms the effectiveness of the compression systems studied.

  • Pressure measurements were conducted over a full 96-hour period
  • After the initial drop within the first 24 hours, pressures remained stable within therapeutic ranges
  • The authors conclude that 'sustained pressure stability confirms the effectiveness of the systems over 96 hours'
  • The pressure dynamics observed were characterised as initially high, followed by a subsequent drop and final stabilisation

Have a question about this study?

Citation

García J, Ruíz M, Conde M, Ramírez A, Jiménez F, García M, et al.. (2026). Temporal Assessment of Pressure and Stiffness in Compression Therapy for Venous Leg Ulcers: Implications for Clinical Optimization.. International wound journal. https://doi.org/10.1111/iwj.70868