Hormone Therapy

Testosterone replacement therapy is associated with high satisfaction rates: results of a survey study.

TL;DR

62.7% of patients were satisfied with their current TRT regimen, with auto-injectors, subcutaneous pellets, and intramuscular injections associated with significantly increased satisfaction rates.

Key Findings

The majority of patients receiving TRT were satisfied with their current treatment regimen.

  • 62.7% of 140 men surveyed reported satisfaction with their current TRT regimen.
  • The study was conducted at a single institution using an open survey format.
  • Survey questions investigated demographics, symptom burden of TD, TRT regimen, treatment preferences, and treatment satisfaction.

Auto-injector use was associated with the highest satisfaction rates among TRT delivery methods.

  • 91.7% of auto-injector users reported satisfaction with their TRT regimen.
  • Auto-injector use was associated with an odds ratio of 9.3 for satisfaction (p < 0.05).
  • This was the highest satisfaction rate among all delivery methods studied.

Subcutaneous pellet use was associated with high TRT satisfaction rates.

  • 90.0% of subcutaneous pellet users reported satisfaction with their TRT regimen.
  • Subcutaneous pellet use was associated with the highest odds ratio for satisfaction at OR = 15.2 (p < 0.05).

Intramuscular injections were associated with significantly increased TRT satisfaction rates.

  • 67.5% of intramuscular injection users reported satisfaction with their TRT regimen.
  • Intramuscular injection use was associated with an odds ratio of 5.7 for satisfaction (p < 0.05).

The majority of patients indicated a preference for self-administered or home-administered TRT injections.

  • When asked about delivery preferences, most patients preferred injection-based TRT administered by themselves or at home.
  • This preference was noted across the survey population of 140 men.

Treatment efficacy was identified as a significant driving factor when patients evaluated TRT regimens, while cost was not.

  • Patients noted that treatment efficacy was a significant factor in evaluating a TRT regimen.
  • Few patients felt that cost was the most significant factor when evaluating their TRT regimen.

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Citation

Loeb C, Miller J, Schneider D, Grimaud L, Moukhtar Hammad M, Yafi F. (2024). Testosterone replacement therapy is associated with high satisfaction rates: results of a survey study.. International journal of impotence research. https://doi.org/10.1038/s41443-023-00724-2