The effect of artificial gravity on the outcome of a two-week resistance vibration exercise programme: BRAVE study.

All three exercise groups showed significant improvements in eight-repetition maximum squat strength after the 2-week training programme.

• Participants (n=24) were divided into three groups: URVE (upright loaded squat), HRVE (horizontal loaded squat), and AGRVE (loaded squat on short-arm human centrifuge).
• Improvement in 8RM squat strength was statistically significant (P < 0.0001) with a large effect size (G > 0.80) across all groups.
• All participants followed the same protocol and were exposed to the same ground reaction force.
• The training period lasted 2 weeks.

Only the AGRVE group demonstrated an improvement in jump height following the 2-week training programme.

• The AGRVE group showed a small effect in jump height (G = 0.26).
• The HRVE and URVE groups did not demonstrate comparable improvements in jump height.
• Muscular power was assessed using a jump test.
• The effect size for jump height in AGRVE was characterized as small (G = 0.26).

The AGRVE group significantly increased knee extension and flexion maximum voluntary contraction (MVC), while HRVE and URVE groups showed no comparable changes.

• Knee extension and flexion MVC were measured using isokinetic dynamometry.
• Significant increases in both knee extension and flexion MVC were observed in the AGRVE group.
• No comparable changes in knee extension or flexion MVC were found in the HRVE or URVE groups.
• This finding indicates that the addition of artificial gravity via a short-arm human centrifuge provided superior neuromuscular adaptation compared to the other two conditions.

The AGRVE group significantly increased total thigh muscle volume with notable hypertrophy in specific muscles.

• Total thigh muscle volume increased significantly in the AGRVE group (P = 0.03).
• Notable hypertrophy was observed in the vastus medialis, semitendinosus, and vastus intermedius muscles.
• Muscle volume was assessed using functional muscle magnetic resonance imaging.
• No comparable increases in thigh muscle volume were reported for the HRVE or URVE groups.

The study evaluated the feasibility and efficacy of combining resistance vibration exercise with artificial gravity delivered via a short-arm human centrifuge.

• The AGRVE condition involved loaded squat exercise conducted on a short-arm human centrifuge.
• All groups performed bilateral squats, triple extension squats, and single/bilateral calf raises.
• Body composition was assessed with dual-energy X-ray absorptiometry (DXA).
• The study involved n=24 participants divided equally among the three groups.
• The training programme duration was 2 weeks.