Body Composition

The Impact of an Exercise Program on Health-related Quality of Life (SarQoL) in Patients with Preoperative Sarcopenic Obesity After Bariatric Surgery: A Randomized Controlled Trial.

TL;DR

A structured 16-week combined aerobic and resistance exercise program after bariatric surgery produced significantly greater increases in health-related quality of life (SarQoL) compared to control in patients with preoperative sarcopenic obesity.

Key Findings

Both intervention and control groups showed increased health-related quality of life after bariatric surgery, but the increase was significantly greater in the exercise intervention group.

  • HRQoL was measured using the Sarcopenia Quality of Life (SarQoL) questionnaire
  • The exercise program lasted 16 weeks and included combined aerobic and resistance exercise
  • All participants underwent Roux-en-Y gastric bypass (RYGB) surgery
  • The increase in HRQoL was significantly greater in the intervention group than in the control group

All study participants met diagnostic criteria for both moderate/severe obesity and sarcopenia at baseline.

  • Sarcopenia was defined according to ESPEN/EASO criteria
  • Criteria included reduced muscle strength assessed by grip strength and reduced muscle mass assessed by ASMM score/weight
  • Baseline characteristics were not significantly different between the two groups
  • All patients met criteria for moderate/severe obesity

The EXPOBAR program used a randomized controlled trial design to evaluate the effectiveness of structured exercise on HRQoL in post-bariatric surgery patients with sarcopenic obesity.

  • Patients were randomized into experimental and control groups
  • The study is registered at ClinicalTrials.gov (NCT05289219)
  • Outcomes measured included body composition and physical fitness parameters before and after the intervention
  • The intervention consisted of a 16-week structured physical exercise program initiated after surgery

Sarcopenia is described as very common in patients with obesity and can be aggravated by bariatric surgery, potentially compromising clinical results.

  • Sarcopenia is characterized by a decrease in muscle mass and strength
  • Bariatric surgery may aggravate sarcopenia in patients with obesity
  • This aggravation can potentially compromise the clinical results of surgery
  • The study aimed to provide evidence-based recommendations for improving quality of life in this population

The authors conclude that exercise is crucial in improving both physical and psychological well-being in post-bariatric patients.

  • Findings highlight the need to integrate structured exercise programs in post-surgery care
  • The exercise program addressed both physical and psychological dimensions of well-being
  • The study aimed to assess effectiveness of exercise on HRQoL as evaluated by the SarQoL questionnaire
  • Results support evidence-based recommendations for exercise integration in post-bariatric care

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Citation

Mendes C, Carvalho M, Bravo J, Martins S, Zangão O, Raimundo A. (2025). The Impact of an Exercise Program on Health-related Quality of Life (SarQoL) in Patients with Preoperative Sarcopenic Obesity After Bariatric Surgery: A Randomized Controlled Trial.. Obesity surgery. https://doi.org/10.1007/s11695-025-08326-1