The Impact of an Exercise Program on Health-related Quality of Life (SarQoL) in Patients with Preoperative Sarcopenic Obesity After Bariatric Surgery: A Randomized Controlled Trial.
Mendes C, Carvalho M, et al. • Obesity surgery • 2025
A structured 16-week combined aerobic and resistance exercise program after bariatric surgery produced significantly greater increases in health-related quality of life (SarQoL) compared to control in patients with preoperative sarcopenic obesity.
Key Findings
Results
Both intervention and control groups showed increased health-related quality of life after bariatric surgery, but the increase was significantly greater in the exercise intervention group.
HRQoL was measured using the Sarcopenia Quality of Life (SarQoL) questionnaire
The exercise program lasted 16 weeks and included combined aerobic and resistance exercise
All participants underwent Roux-en-Y gastric bypass (RYGB) surgery
The increase in HRQoL was significantly greater in the intervention group than in the control group
Results
All study participants met diagnostic criteria for both moderate/severe obesity and sarcopenia at baseline.
Sarcopenia was defined according to ESPEN/EASO criteria
Criteria included reduced muscle strength assessed by grip strength and reduced muscle mass assessed by ASMM score/weight
Baseline characteristics were not significantly different between the two groups
All patients met criteria for moderate/severe obesity
Methods
The EXPOBAR program used a randomized controlled trial design to evaluate the effectiveness of structured exercise on HRQoL in post-bariatric surgery patients with sarcopenic obesity.
Patients were randomized into experimental and control groups
The study is registered at ClinicalTrials.gov (NCT05289219)
Outcomes measured included body composition and physical fitness parameters before and after the intervention
The intervention consisted of a 16-week structured physical exercise program initiated after surgery
Background
Sarcopenia is described as very common in patients with obesity and can be aggravated by bariatric surgery, potentially compromising clinical results.
Sarcopenia is characterized by a decrease in muscle mass and strength
Bariatric surgery may aggravate sarcopenia in patients with obesity
This aggravation can potentially compromise the clinical results of surgery
The study aimed to provide evidence-based recommendations for improving quality of life in this population
Conclusions
The authors conclude that exercise is crucial in improving both physical and psychological well-being in post-bariatric patients.
Findings highlight the need to integrate structured exercise programs in post-surgery care
The exercise program addressed both physical and psychological dimensions of well-being
The study aimed to assess effectiveness of exercise on HRQoL as evaluated by the SarQoL questionnaire
Results support evidence-based recommendations for exercise integration in post-bariatric care
Mendes C, Carvalho M, Bravo J, Martins S, Zangão O, Raimundo A. (2025). The Impact of an Exercise Program on Health-related Quality of Life (SarQoL) in Patients with Preoperative Sarcopenic Obesity After Bariatric Surgery: A Randomized Controlled Trial.. Obesity surgery. https://doi.org/10.1007/s11695-025-08326-1