Dietary Supplements

The role of intestinal microflora in prehabilitation for colorectal cancer surgery - systematic review.

TL;DR

This systematic review assessed the role of probiotics in prehabilitation of patients scheduled for colorectal cancer surgery, finding that probiotics administered perioperatively may improve surgical outcomes by modulating intestinal microflora, though the evidence is not yet definitive.

Key Findings

Prehabilitation has been recognized as an effective approach to improve surgical outcomes in colorectal cancer patients.

  • Prehabilitation is described as 'a strategy designed to enhance patients' health status prior to surgery'
  • The review specifically focuses on colorectal cancer, which is characterized as 'a global health issue that frequently necessitates surgical treatment'
  • Probiotics were identified as 'a potential component of prehabilitation regimens for CRC patients'

Probiotics have a positive impact on gut health and may play a role in prehabilitation for colorectal cancer surgery through modulation of intestinal microflora.

  • Probiotics are described as 'celebrated for their positive impact on gut health'
  • The review examines the specific role of intestinal microflora in the context of surgical prehabilitation
  • The systematic review was 'intended to assess the role of probiotics in the prehabilitation of patients scheduled for colorectal cancer surgery'

The evidence supporting the efficacy of probiotics in the prehabilitation setting for colorectal cancer surgery is not yet definitive.

  • The authors explicitly state that 'the evidence supporting their efficacy in this setting is not yet definitive'
  • A systematic review methodology was employed to evaluate the available evidence
  • The inconclusive nature of the evidence suggests further research is needed in this area

Have a question about this study?

Citation

Prusisz M, Włodarczyk J, Bilińska I, Porc M, Maryńczak K, Włodarczyk M, et al.. (2026). The role of intestinal microflora in prehabilitation for colorectal cancer surgery - systematic review.. Polski przeglad chirurgiczny. https://doi.org/10.5604/01.3001.0055.2587