Sleep

The role of sleep efficiency in 24-h blood pressure variability.

TL;DR

Among adults with elevated blood pressure, better sleep efficiency, but not longer sleep duration or perceived sleep quality, was linked to lower short-term blood pressure variability.

Key Findings

Higher actigraphy-derived sleep efficiency was significantly associated with lower systolic and diastolic blood pressure variability.

  • Association was statistically significant for both systolic and diastolic BPV (P < 0.05)
  • After additional adjustment for BMI, the diastolic association remained significant (P = 0.003) and the systolic association became marginal (P = 0.056)
  • Linear regression models were adjusted for age, sex, and race as covariates
  • BPV was quantified as the average real variability of systolic and diastolic pressures derived from 24-h ambulatory blood pressure monitoring

Total sleep time was not independently associated with blood pressure variability.

  • TST was measured objectively via wrist actigraphy over seven days
  • No statistically significant relationship was found between TST and either systolic or diastolic BPV
  • Participants were recruited based on self-reported short sleep of less than 7 hours per night

Subjective sleep measures were not independently related to blood pressure variability.

  • Three subjective measures were assessed: the Insomnia Severity Index, PROMIS Sleep Disturbance scale, and PROMIS Sleep-Related Impairment scale
  • None of the subjective sleep measures showed a statistically significant independent relationship with BPV
  • This contrasted with the objective measure of sleep efficiency, which was significantly associated with BPV

Hourly BPV profiles showed peak blood pressure variability during early morning and late afternoon periods.

  • 24-h ambulatory blood pressure monitoring was used to characterize hourly BPV profiles
  • Two distinct peak periods were identified: early morning and late afternoon
  • This diurnal pattern was observed across the study sample

The study enrolled 200 adults with elevated clinic blood pressure and self-reported short sleep in a cross-sectional baseline analysis.

  • Mean participant age was 42 ± 11 years
  • Inclusion criteria required clinic blood pressure of 120–150/80–90 mmHg and self-reported sleep duration less than 7 hours per night
  • Age range was 18–65 years
  • Data were collected as baseline measurements from a behavioral sleep-extension trial
  • Seven days of wrist actigraphy and one 24-h ambulatory blood pressure monitoring session were completed by each participant

What This Means

This research suggests that the quality of sleep — specifically how efficiently a person sleeps — may be more important than how long they sleep when it comes to blood pressure stability throughout the day. The study followed 200 adults who had mildly elevated blood pressure and reported sleeping less than 7 hours per night. Participants wore wrist devices to track sleep objectively for a week and also wore blood pressure monitors for 24 hours. The researchers found that people who slept more efficiently (spending a higher proportion of time in bed actually asleep) had less fluctuation in their blood pressure over the course of the day. Interestingly, total sleep time and how people subjectively felt about their sleep quality did not show the same relationship. Blood pressure variability — how much blood pressure rises and falls throughout the day — is known to be an independent risk factor for heart attacks and strokes, separate from average blood pressure levels. This study found that the peaks in blood pressure variability tended to occur in the early morning and late afternoon. The finding that sleep efficiency, rather than sleep duration or perceived sleep quality, was the key factor associated with lower variability suggests that the two concepts measure something meaningfully different. This research suggests that interventions designed to improve sleep efficiency, such as behavioral therapies that reduce time spent awake in bed, could potentially offer cardiovascular benefits beyond simply encouraging people to sleep longer. It also highlights that how well someone sleeps, as objectively measured, may not match how they perceive their own sleep quality, and that both dimensions may matter differently for health outcomes.

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Citation

Landvatter J, Bress A, Duffecy J, Conroy M, Simonsen S, Baron K. (2026). The role of sleep efficiency in 24-h blood pressure variability.. Journal of hypertension. https://doi.org/10.1097/HJH.0000000000004222