Cardiovascular

Treatment Adherence and its Association with Demographic Characteristics and Clinical Factors Among Patients with Hypertension: A Cross-Sectional, Descriptive-Correlational Study.

TL;DR

Most patients with hypertension in Semnan health centers were adherent to treatment (77.5%), and no demographic or clinical characteristics were significantly associated with adherence.

Key Findings

Most hypertensive patients in the Semnan health center sample were classified as adherent to treatment.

  • Overall, 77.5% (95%CI: 73.4%-81.6%) of the patients were adherent to treatment, defined as a score ≥86.
  • The sample comprised 400 patients with high blood pressure selected by multistage sampling.
  • Data were collected in 2024 using demographic information and treatment adherence questionnaires after informed consent.

The mean treatment adherence score was 83.8 out of 115.

  • Mean ± SD adherence score was 83.8 ± 12.4 (out of 115).
  • The median score was 89.6, higher than the mean, indicating a left-skewed distribution.
  • The adherence cut-off was a score of 86 or above.

Treatment adherence was not significantly associated with any of the demographic characteristics examined.

  • Non-significant (p > 0.05) variables included age, gender, body mass index, marital status, educational level, employment status, number of children, and income level.
  • Participants had a mean ± SD age of 48.2 ± 18.2 years (median 49), and 54.3% were female.

Treatment adherence was not significantly associated with clinical or medication-related factors.

  • Non-significant (p > 0.05) variables included medical history, blood pressure, medication-related variables, duration of hypertension, duration of antihypertensive treatment, and other comorbidities.

The authors conclude that patient education about lifestyle modification should be prioritized by policymakers and healthcare planners.

  • They cite evidence that knowledge influences patients' health behaviors.
  • Education is proposed for the prevention, management, and control of hypertension.

The study has several acknowledged limitations.

  • Reliance on self-reported data.
  • Cross-sectional design, which limits causal inference.
  • Limited generalizability of the findings.

What This Means

This study surveyed 400 people with high blood pressure who attended health centers in Semnan, Iran, in 2024. Participants filled out a questionnaire measuring how well they followed their treatment, scored out of 115. About 77.5% scored high enough to be counted as adherent, and the average score was 83.8. The researchers looked for factors that might explain who followed treatment better, including age, gender, body weight, marital status, education, job, income, how long people had had high blood pressure, how long they had taken medication, their blood pressure readings, and other health conditions. None of these showed a statistically significant link with adherence. This suggests that adherence in this group was not easily predicted by basic personal or clinical characteristics. The authors suggest that educating patients about lifestyle changes could help with preventing and controlling hypertension, since knowledge influences health behavior. However, the study relied on self-reported answers, captured only one point in time, and involved patients from one area, so the results may not apply elsewhere and cannot show cause and effect.

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Citation

Vafaei A, Ghorbani R, Zarvani P, Nobahar M. (2026). Treatment Adherence and its Association with Demographic Characteristics and Clinical Factors Among Patients with Hypertension: A Cross-Sectional, Descriptive-Correlational Study.. Vascular health and risk management. https://doi.org/10.2147/VHRM.S646427