Cardiovascular

Unusual renal vascular adaptations in childhood Takayasu arteritis: a CT angiographic demonstration of extensive collaterals and aberrant arteries.

TL;DR

A young Indian male with childhood Takayasu arteritis developed extensive collateral and accessory renal arteries as adaptive vascular remodelling, with preserved renal function, highlighting the role of CT angiography in delineating complex vascular remodelling in chronic TA.

Key Findings

A young Indian male with Takayasu arteritis presented with resistant hypertension and bilateral renal artery stenosis.

  • The patient is described as a young Indian male, which is noted as unusual since TA typically affects young females.
  • The patient had resistant hypertension as a primary clinical manifestation.
  • Bilateral renal artery stenosis was identified as the underlying vascular pathology.
  • The case represents a rare constellation of findings, particularly in a male patient.

The patient developed extensive collateral and accessory renal arteries as adaptive vascular remodelling in the setting of chronic, inactive large-vessel vasculitis.

  • The vascular remodelling is described as 'extensive collateral and accessory renal arteries.'
  • The vasculitis was characterized as chronic and inactive at the time of imaging.
  • The remodelling is described as 'adaptive vascular remodelling' in response to the underlying stenotic disease.
  • This constellation of extensive collateralisation in the context of TA is described as rare.

Renal function was preserved due to extensive collateralisation despite bilateral renal artery stenosis.

  • The paper states renal function was preserved 'due to extensive collateralisation.'
  • This finding suggests that robust collateral vessel development can compensate for bilateral main renal artery stenosis in chronic TA.
  • The preservation of renal function in the setting of bilateral renal artery stenosis is highlighted as a notable aspect of this case.

CT angiography was instrumental in delineating the complex vascular remodelling in this case of chronic Takayasu arteritis.

  • The paper underscores 'the role of CT angiography in delineating complex vascular remodelling in chronic TA.'
  • CT angiography demonstrated both the bilateral renal artery stenosis and the extensive collateral and aberrant arteries.
  • The imaging findings are described as an 'unusual' and complex vascular anatomy warranting CT angiographic demonstration.
  • The authors emphasize 'the importance of early imaging in young individuals with unexplained hypertension.'

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Citation

Dhamija A, Malhi A. (2026). Unusual renal vascular adaptations in childhood Takayasu arteritis: a CT angiographic demonstration of extensive collaterals and aberrant arteries.. BMJ case reports. https://doi.org/10.1136/bcr-2025-270427