Risk factors such as occupational satisfaction, health, and family relations significantly influence PHW mental health in China, with notable differences by urbanicity, and tailored mental health interventions are recommended to address urban-rural disparities.
Key Findings
Methods
The study recruited 3,769 primary healthcare workers across all 31 provinces in mainland China, with the majority working in rural settings.
1,006 (26.7%) PHWs worked in urban areas and 2,763 (73.3%) worked in rural areas
Participants were recruited from 44 urban community health service centers and 27 rural township hospitals
Data collection occurred between 1 May and 31 October 2022
Workers included family physicians, nurses, public health professionals, pharmacists, and other medical staff
The Bayesian Additive Regression Tree (BART) model was employed to identify risk factors
Results
Occupational satisfaction significantly influenced anxiety in both urban and rural primary healthcare workers.
Occupational satisfaction was identified as a key factor for anxiety across both urban and rural settings
The BART model was used to identify this as a shared determinant regardless of urbanicity
Occupational satisfaction was also associated with depression for all PHWs
Results
Living with family was a significant protective factor against anxiety and depression specifically for urban primary healthcare workers.
For urban PHWs, living with family was associated with reduced anxiety (OR: 0.42, 95% CI: 0.28–0.62)
Living with family was also associated with reduced depression in urban PHWs (OR: 0.51, 95% CI: 0.34–0.75)
This factor was identified as a key determinant specifically for urban, not rural, practitioners
Results
Self-rated health was a significant protective factor against anxiety for urban primary healthcare workers.
Fair self-rated health was associated with reduced anxiety in urban PHWs (OR: 0.31, 95% CI: 0.23–0.42)
Good self-rated health was associated with even greater reduction in anxiety (OR: 0.13, 95% CI: 0.09–0.20)
Self-rated health was also associated with depression for all PHWs
Results
After-work exercise played a critical role in anxiety specifically for rural primary healthcare workers.
Rare after-work exercise was associated with reduced anxiety in rural PHWs (OR: 0.28, 95% CI: 0.11–0.76)
Frequent after-work exercise was associated with further reduced anxiety in rural PHWs (OR: 0.15, 95% CI: 0.05–0.44)
After-work exercise was also associated with depression for all PHWs
This factor was identified as a key determinant specifically for rural practitioners
Results
Organizational support satisfaction was a significant protective factor against depression specifically for urban primary healthcare workers.
Being satisfied with organizational support was associated with reduced depression in urban PHWs (OR: 0.28, 95% CI: 0.19–0.42)
This factor was identified as significant for urban practitioners specifically
Organizational support satisfaction was not highlighted as a key factor for rural PHWs
Results
Depression was associated with after-work exercise, self-rated health, and occupational satisfaction across all primary healthcare workers regardless of urbanicity.
These three factors were identified as common determinants of depression for both urban and rural PHWs
Additionally, living with family (OR: 0.51, 95% CI: 0.34–0.75) and organizational support satisfaction (OR: 0.28, 95% CI: 0.19–0.42) were significant specifically for urban practitioners
The BART model was used to identify these associations
Huang J, Yang Y, Chu Y, Zhu P, Liang H, Gu J, et al.. (2026). Urban-rural differences in determinants of mental health among primary healthcare workers in China.. Epidemiology and psychiatric sciences. https://doi.org/10.1017/S2045796025100425