Cardiovascular

Venous thromboembolism-related readmission after ventral hernia repair in the United States: a propensity score-matched analysis of open and minimally invasive surgery and insights from a national database.

TL;DR

After propensity score matching, the surgical approach (open vs. minimally invasive) was not a significant predictor of VTE-related readmission following ventral hernia repair, while patient-related factors such as age >65 years and discharge with home healthcare were independent predictors.

Key Findings

After propensity score matching, the difference in 30-day VTE-specific readmission rates between open and MIS ventral hernia repair was not statistically significant.

  • Post-matching rates: Open 1.98% vs. MIS 2.37%
  • OR 1.19, 95% CI 0.97–1.46, p = 0.088
  • Propensity score matching yielded a matched cohort of n = 418,846 patients
  • The surgical approach was not a significant predictor of VTE-related readmission

MIS approach was significantly associated with lower odds of all-cause 30-day readmission compared to open surgery.

  • OR 0.76, 95% CI 0.74–0.78, p < 0.001
  • This finding was based on the propensity score-matched cohort of 418,846 patients
  • Analysis was conducted using the Nationwide Readmissions Database (NRD) from 2016 to 2022

MIS approach was associated with shorter hospital length of stay compared to open surgery.

  • MIS: 4.35 days vs. Open: 5.35 days, p < 0.001
  • Difference of approximately 1 day in length of stay
  • Analysis performed after propensity score matching to balance baseline characteristics

MIS approach was associated with slightly lower total inpatient hospitalization costs compared to open surgery.

  • MIS: $22,315 vs. Open: $23,304, p < 0.001
  • Difference of approximately $989 in hospital costs
  • Cost was a secondary outcome of the study

Age greater than 65 years was an independent predictor of VTE-specific readmission after ventral hernia repair.

  • OR 1.84, p = 0.001
  • Identified through multivariable analysis as an independent predictor
  • Patient-related factors rather than surgical approach were associated with VTE-related readmissions

Discharge with home healthcare was an independent predictor of VTE-specific readmission after ventral hernia repair.

  • p = 0.026 for discharge with home healthcare as a predictor
  • Identified alongside age >65 years as an independent patient-related predictor
  • The relative contribution of individual patient factors could not be determined due to lack of granular data within the NRD dataset

The original unmatched cohort consisted of 834,298 patients undergoing ventral hernia repair, with a substantial majority having open surgery.

  • Total cohort: 834,298 patients identified from the NRD 2016–2022
  • Open surgery: 74.5% of patients
  • MIS surgery: 25.5% of patients
  • Propensity score matching was performed to minimize selection bias and balance baseline characteristics

What This Means

This research examined whether the type of surgical approach—traditional open surgery versus minimally invasive surgery (MIS, such as laparoscopic or robotic techniques)—affects the risk of being readmitted to the hospital within 30 days due to blood clots (venous thromboembolism, or VTE) after ventral hernia repair. Using a large U.S. national database covering 2016 to 2022, the researchers studied over 834,000 patients and used a statistical technique called propensity score matching to fairly compare open and MIS patients who were otherwise similar in health status and risk factors. After matching, the study found no statistically significant difference in VTE-related readmission rates between the two surgical approaches (about 2.0% for open vs. 2.4% for MIS). However, MIS was associated with meaningful benefits in other areas: patients who had MIS were less likely to be readmitted for any reason, had shorter hospital stays (about one day less), and had slightly lower hospital costs. The factors most strongly linked to VTE readmission were patient-related: being over age 65 and being sent home with home healthcare services after surgery, not the type of surgery performed. This research suggests that choosing between open and minimally invasive hernia repair should not be driven by concerns about blood clot risk, as both approaches carry similar VTE readmission rates when patients are comparable. Instead, efforts to reduce post-surgical blood clots should focus on identifying and closely managing high-risk patients—particularly older individuals and those requiring home healthcare after discharge. The authors note that future studies with more detailed patient data are needed to better understand which specific risk factors contribute most to VTE after hernia surgery.

Have a question about this study?

Citation

Boyal N, da Silveira C, Kang P, Premkumar A, Horiuchi S, Rasador A, et al.. (2026). Venous thromboembolism-related readmission after ventral hernia repair in the United States: a propensity score-matched analysis of open and minimally invasive surgery and insights from a national database.. Hernia : the journal of hernias and abdominal wall surgery. https://doi.org/10.1007/s10029-026-03777-6