Individuals attending mpox vaccine-only visits at a sexually transmitted infection clinic were more likely to be new patients with high socioeconomic status and identify as White than those vaccinated during non-mpox-related visits, and a small number received HIV preexposure prophylaxis or testing following vaccination, representing a potential missed opportunity for HIV prevention.
Key Findings
Results
Patients attending mpox vaccine-only visits had different demographic characteristics compared to those vaccinated during non-mpox-related visits.
Mpox vaccine-only visit attendees were more likely to be new patients to the clinic
Mpox vaccine-only visit attendees were more likely to have high socioeconomic status
Mpox vaccine-only visit attendees were more likely to identify as White compared to those vaccinated during non-mpox-related visits
Results
A small number of individuals who received mpox vaccination subsequently received HIV preexposure prophylaxis (PrEP) or HIV testing.
The low uptake of PrEP and HIV testing following mpox vaccination was noted as a potential missed opportunity for HIV prevention
The study was conducted at an urban specialized sexual health/sexually transmitted infection clinic
The finding suggests that mpox vaccination visits may not have been effectively leveraged to deliver HIV prevention services
Results
The type of clinic visit (mpox vaccine-only versus non-mpox-related) was associated with differences in patient characteristics relevant to healthcare equity.
New patients were disproportionately represented among mpox vaccine-only visit attendees
Socioeconomic status and racial identity differed significantly between the two visit type groups
These demographic differences suggest that mpox vaccination may have attracted a patient population not previously engaged with sexual health services at the clinic
The findings raise questions about equitable access to and engagement with HIV prevention services across different patient groups
Discussion
Mpox vaccine-only visits at a sexual health clinic represented a potential opportunity to link patients to HIV prevention services that was largely not realized.
The study was conducted at an urban specialized sexual health clinic
HIV prevention services considered included HIV PrEP and HIV testing
The authors characterize the low linkage to HIV prevention as a 'missed opportunity'
Mpox vaccination visits could serve as an entry point for broader sexual health services for new patients
What This Means
This research examined patients who came to an urban sexual health clinic specifically for mpox (monkeypox) vaccination and compared them to patients who received mpox vaccination as part of a broader clinic visit for other reasons. The study found that people who came solely for mpox vaccination tended to be new to the clinic, had higher socioeconomic status, and were more likely to identify as White, compared to those vaccinated during other types of visits. This suggests that the mpox vaccine rollout may have reached a somewhat different — and more socioeconomically privileged — population than the clinic's usual patient base.
The study also found that very few of the people who got mpox vaccinations went on to receive HIV prevention services such as pre-exposure prophylaxis (PrEP) or HIV testing at the clinic. Since mpox and HIV share overlapping at-risk populations and transmission networks, the authors suggest that vaccination visits could have been used as an opportunity to offer these additional prevention tools, but this largely did not happen.
This research suggests that sexual health clinics offering mpox vaccination could do more to integrate HIV prevention services into those visits, potentially reaching people who might not otherwise engage with HIV prevention. It also highlights potential disparities in who accessed mpox vaccination through specialized clinics, which could inform more equitable outreach strategies in future public health responses.
Shah P, Germain C, Ard K, Parker R, Bassett I, Jarolimova J. (2026). Visit Types and Linkage to HIV Prevention Among Individuals Seeking Mpox Vaccination in an Urban Specialized Sexual Health Clinic.. Sexually transmitted diseases. https://doi.org/10.1097/OLQ.0000000000002222