Sleep
445 peer-reviewed studies indexed
Early Drowsiness Detection via Second-Order Derivative Analysis of Heart Rate Variability: A Non-Contact ECG Approach with Machine Learning.
First and second derivatives of heart rate variability, recorded via non-contact capacitive ECG electrodes, detected pre-crash drowsy states 6.8 ± 2.3 minutes before crash events, with a combined HRV feature set achieving AUC = 0.863, though derivatives alone (AUC = 0.573) served as complementary rather than standalone predictors.
Connected Embedded System for Drowsiness Detection Based on a Reconfigurable Set of Features.
A single-channel EEG-based drowsiness detection system using IoT technology and a reconfigurable set of five power spectral density features achieved 95% accuracy in detecting driver drowsiness while overcoming interpersonal variability due to aging.
Processing multi-talker speech in a tone language: Dumplings interfere with sleep at a cocktail party.
A robust benefit of talker F0 separation is observed in Mandarin cocktail party listening, but the advantage is constrained by the lexical role of F0, with real-word tonal minimal pairs lowering recognition accuracy relative to baseline.
Moderating role of financial legal satisfaction in the relationship between business environment and health outcomes among Chinese financial professionals: a cross-sectional study.
Financial legal satisfaction plays a critical moderating role in the relationship between business environment and health outcomes among Chinese financial professionals, weakening the positive link with subjective health and amplifying the negative association with psychological stress.
Effect of adjunctive perampanel on daytime sleepiness and quality of life in adults with focal-onset seizures: Post hoc analyses of the AMPA study.
Adjunctive perampanel did not worsen daytime sleepiness over ≤12 months, and in a small subset of patients, seizure frequency was reduced regardless of ESS changes, while mean QoL at end of treatment was improved for those without excessive daytime sleepiness but declined for those with excessive daytime sleepiness.
HairTime: A noninvasive assay for estimating circadian phase from a single hair sample.
HairTime, a noninvasive assay estimating circadian phase from a single daytime hair sample, demonstrated strong predictive power compared to dim-light melatonin onset (DLMO) and revealed associations between circadian phase and age, sex, and work schedules across over 4,000 samples.
The clinical and cost-effectiveness of improving sleep via carer delivered strategies in people with dementia: the DREAMS START parallel multi-centre RCT.
DREAMS START plus treatment as usual is clinically effective in reducing sleep disturbance in people living at home with dementia at 8 months, demonstrating sustained effectiveness beyond intervention delivery, and is likely to be cost-effective when delivered by non-clinically trained graduates.
Effects of a 90-Min Nap on Time-Motion Metrics and Psychophysiological Responses During Small-Sided Games in Professional Soccer Players.
A 90-min nap before small-sided games training increased total distance covered, reduced perceived fatigue, and enhanced mood, wellness, and cognitive alertness in professional soccer players.
Development of a Validation and Inspection Tool for Armband-based Lifelog data (VITAL) to facilitate the clinical use of wearable health data: A prototype and usability evaluation.
VITAL demonstrated the feasibility of harmonizing, visualizing, and evaluating wearable health data for clinical use, with findings suggesting the tool is practical and valuable for supporting clinical workflows.
[Mechanism of Wuyou Decoction in improving hippocampal injury in chronic sleep deprivation model rats by inhibiting neuroinflammation and protecting blood-brain barrier].
Wuyou Decoction improves cognitive function in chronic sleep deprivation model rats by inhibiting the release of pro-inflammatory cytokines and protecting the integrity of the blood-brain barrier.
Effect of melatonin versus placebo for the prevention of delirium among medically hospitalised older patients: a double-blinded randomised controlled trial (project RESTORE).
Melatonin did not significantly reduce the incidence of delirium among medically hospitalised older patients compared to placebo, and the trial was terminated early due to futility.
Psychological and Sleep Changes in Pre-Selected Members of the Polar Inland Expedition Team During Rapid Ascent High-Altitude Training.
A multimodal assessment protocol revealed that Antarctic inland expedition candidates undergoing rapid high-altitude training exhibited altitude-dependent sleep fragmentation, exacerbated anxiety under acute hypoxia, and preserved working memory at 3,700 m mediated by compensatory prefrontal activation.
Effects of Noise Reduction Protocol-Based Integrated Nursing Care on Perceived Comfort Level and Physiological and Psychological Stress Responses in Patients with Gastrointestinal Tumors.
Noise reduction protocol-based integrated nursing care effectively reduces environmental noise exposure in patients with gastrointestinal tumors and is associated with decreased psychological stress, improved sleep quality, and enhanced perceived comfort and quality of life.
Treadmill Test and Ambulatory Blood Pressure Monitoring: Can They Be Performed on the Same Day? Can the Effort Reached on the Treadmill Interfere?
Performing the exercise stress test and ABPM on the same day did not affect ABPM blood pressure values, and the intensity reached during the test, whether submaximal or maximal, did not influence ABPM results.
When the outcome is compositional: A method for conducting compositional response linear mixed models for physical activity, sedentary behaviour and sleep research.
A practical framework for implementing a compositional multivariate-response linear mixed model is provided that can model the entire 24-hour movement-behaviour composition as the dependent variable within a multilevel framework, with results invariant to the chosen log-ratio basis.
Quantifying the effect of Behaviour Self-Regulation on well-being through causal analysis: A methodological framework for longitudinal health data.
Short-term behavioural consistency demonstrates a significantly stronger causal impact on daily well-being than long-term self-regulation, despite a near-zero correlation, and causally-informed feature selection significantly improves predictive accuracy of well-being in machine learning models compared to conventional methods.
Association Between Attitude Toward a Healthy Lifestyle, Lifestyle Behaviors, Sociodemographic Characteristics, and Body Mass Index: A Cross-Sectional Study.
Attitude toward a healthy lifestyle is significantly associated with lifestyle behaviors, BMI, excess body weight, and self-rated health, highlighting the importance of psychological factors in promoting sustainable healthy lifestyles.
Effect of an internet-based, mobile terminal-supported, family-participatory early rehabilitation model on sleep improvement and stigma prevention in critically ill patients: A randomized controlled trial.
An internet-based, family-participatory early rehabilitation model significantly improves sleep architecture, reduces perceived social stigma, and alleviates procedural pain in critically ill patients, representing a promising non-pharmacological strategy to enhance recovery in the ICU.
Transauricular vagus nerve electrical stimulation improves postoperative sleep disorders in elderly patients (VNstep): protocol for a randomized controlled clinical trial.
This protocol describes a single-center, prospective, randomized controlled clinical trial designed to investigate the efficacy and feasibility of transauricular vagus nerve stimulation (taVNS) in improving perioperative sleep disorders in elderly patients receiving general anesthesia.
[Effect of electroacupuncture on neuronal autophagy in rats with chronic sleep deprivation via the PI3K/AKT/mTOR signaling pathway].
Electroacupuncture at Fengchi (GB20) and Gongxue (Extra) could promote dendritic spine formation, enhance synaptic plasticity, and improve cognitive function in rats with chronic sleep deprivation, and these effects may be related to the inhibition of the PI3K/AKT/mTOR signaling pathway and activation of hippocampal neuronal autophagy.
Glossopharyngeal airway collapse is the main factor leading REM-related oxygen desaturation in patients with obstructive sleep apnea: a pilot study.
Glossopharyngeal airway narrowing is the leading factor of REM-related oxygen desaturation in patients with moderate or severe OSA by the prolongation of apnea events during REM sleep.
The role of resting-state functional connectivity of locus coeruleus in attention decline after acute sleep deprivation.
Resting-state functional connectivity between the locus coeruleus and the left caudal temporal thalamus was correlated with attention performance and attention decline after acute sleep deprivation, suggesting a potential LC-thalamus-attention mechanism associated with sleep loss.
Application and efficacy of pain combined with psychological intervention nursing in patients with craniocerebral trauma combined with ocular trauma after decompressive craniectomy.
Pain nursing combined with psychological intervention nursing could significantly improve pain level, sleep quality, negative psychology, psychological resilience, self-care ability, and nursing satisfaction in patients with traumatic brain injury and eye injury undergoing decompressive craniectomy, with greater improvement than psychological intervention nursing alone.
24-hour movement behaviours and cardiometabolic health in adults with type 2 diabetes: a comparative cross-sectional and longitudinal analysis.
Adults with T2DM have a less favourable 24-hour movement behaviour composition compared to adults without T2DM, and no significant changes in movement behaviours were found after 1-year or 2-year follow-up among adults with T2DM.
The Effect of 4-7-8 Breathing Exercise Technique on Tinnitus Handicap, Psychological Factors, and Sleep Quality in Tinnitus Patients: A Randomized Controlled Study.
4-7-8 breathing exercises performed for 6 weeks resulted in significant decreases in tinnitus handicap, anxiety, perceived stress, and sleep quality scores compared to a control group that received only an informative session.
Dynamic Sleep-Derived Heart Rate and Heart Rate Variability Features Associated with Glucose Metabolism Status: An Exploratory Feature-Selection Study Using Consumer Wearables.
Dynamic features capturing overnight trends and variability patterns of heart rate and HRV during sleep—derived from a consumer Fitbit device—showed stronger associations with nocturnal mean glucose than conventional static mean values, with two dynamic HRV features differing significantly between lower- and higher-glycemic-risk groups.
Automatic EEG-based dream-related emotion recognition using fuzzy entropy and efficient signal decomposition methods.
An automated EEG-based framework using Empirical Mode Decomposition combined with Fuzzy Entropy and K-Nearest Neighbors classifier achieved 92.33% accuracy for multi-class dream emotion recognition from REM sleep signals.
DrowsyDG-Phys: Generalizable driver drowsiness estimation in conditional automated vehicles using physiological signals.
DrowsyDG-Phys, a novel domain generalization framework using physiological signals, achieves 78.5% accuracy on the domain generalization protocol and 88.4% accuracy on the cross-subject protocol for driver drowsiness detection, outperforming baseline methods.
Mediating Role of Building Vibration Noise in the Relationship between Housing Type and Mental Health: Evidence from a Taiwanese Online Survey.
Building vibration noise appears to be a key pathway linking living in an apartment/condominium to adverse mental health outcomes, mediating associations with poorer sleep quality, anxiety, depression, and suicide risk.
Diagnostic cutoffs of REM sleep without atonia for identifying isolated REM sleep behavior disorder in a Korean population.
Diagnostic and physiologic RWA cutoffs in Koreans broadly align with Western findings, though discrepancy with earlier Asian cohort data suggests that multinational, multi-ethnic studies are warranted to assess generalizability across Asian populations.
Validation of transcutaneous CO2 measurement in awake children undergoing sleep studies.
PtcCO2 measurements provide a reliable estimation of PcapCO2 in awake, hemodynamically stable children undergoing sleep studies, with a mean bias of -0.59 mmHg and limits of agreement from -5.56 to +4.38 mmHg.
Co-Design of a Sleep Improvement Intervention for Persons Living With Dementia Boarding in the Emergency Department.
Through participatory co-design, multilevel strategies were identified to improve sleep for persons living with dementia boarding in the ED, including reducing environmental stimulation, integrating familiar routines, and enhancing staff dementia training to mitigate sleep disruption and delirium risk.
A randomized, double-blind, crossover study of acute low-level night-time road traffic noise: effects on vascular function, sleep, and proteomic signatures in healthy adults.
Acute exposure to night-time road traffic noise leads to measurable changes in cardiovascular health parameters in healthy adults, with effects linked to activation of molecular pathways of immune signalling and interindividual biological susceptibility.
A Home-Based Intervention to Improve Adherence to the 24-Hour Movement Guidelines in Young Children: Protocol for a Mobile App-Based Randomized Control Trial.
This paper describes the protocol for a 12-week mobile app-based randomized controlled trial designed to evaluate the effectiveness and feasibility of a home-based intervention to improve adherence to the 24-Hour Movement Guidelines in preschoolers who meet zero or one guideline.
Effects of high-intensity interval training on depressive symptoms in Hong Kong community-dwelling older adults with mild to moderate depressive symptoms: a study protocol for a cluster randomized controlled trial.
This paper describes a protocol for a single-blinded, cluster-randomised controlled trial investigating the effects of HIIT on depressive symptoms, biomarkers, physical fitness, sleep quality, and quality of life in Hong Kong community-dwelling older adults with mild to moderate depressive symptoms.
[Bidirectional association of sleep duration and sedentary time with obesity risk among junior high school students].
Bidirectional association between sleep duration and obesity was found among junior high school students, with higher BMI predicting shorter subsequent sleep and shorter sleep predicting higher subsequent BMI.
Effects of 24-h Movement Behaviours on Emotional and Behavioural Problems in Chinese Preschoolers Using Compositional Data Analysis.
Replacing as little as 1 min of MVPA, LPA, or SED with sleep was associated with significant reductions in emotional and behavioural problems in Chinese preschoolers, while increasing sleep by reducing any other movement behaviour was consistently associated with improvements across all SDQ subscales.
Biphasic adaptation of gBOLD-CSF coupling during sleep deprivation reflects compensatory enhancement and temporal disruption in glymphatic function.
36-hour sleep deprivation induces a biphasic modulation of gBOLD-CSF coupling, characterized by a transient enhancement peaking at approximately 30 hours of wakefulness and a concurrent temporal phase shift, reflecting compensatory yet disrupted glymphatic-related dynamics.
Past stories, future worries: sleep does not alter the emotional response to future-relevant or irrelevant negative memories.
Future relevance influences emotional memories independently of sleep, with arousal decreasing over time for future-irrelevant but not future-relevant negative memory cues regardless of whether a sleep or wake interval intervened.
The Common FTO rs9939609 Polymorphism Interacts with Sleeping and Eating Windows to Affect Predisposition to Type 2 Diabetes.
Eating and fasting windows, late last meal timing, hours of night sleep, late bedtime onset, and poorer sleep quality are significantly associated with T2DM risk among FTO rs9939609 risk carriers and may reflect metabolic vulnerability associated with FTO risk alleles.
Impact of Noise Reduction Management on Occupational Protection and Auditory Fatigue in Hospital Central Sterile Supply Department Staff.
Implementation of systematic noise reduction management in hospital CSSD was associated with reduced environmental noise levels, improved occupational protection, alleviation of auditory fatigue, and improvement in sleep quality and overall quality of life among staff members.
Behavioral treatment of insomnia in active-duty service members with traumatic brain injury: study protocol for a randomized clinical trial.
This paper describes the study protocol for a phase II randomized clinical trial evaluating and comparing in-person CBTI versus clinician-supervised digital platform CBTI versus treatment as usual for insomnia in active-duty service members with traumatic brain injury.
The Effect of Preoperative Sleep Quality on Postoperative Delirium in Middle-Aged and Elderly Patients: A Clinical Setting.
Poor preoperative sleep quality in elderly patients is associated with increased risk of postoperative delirium, specifically ICU delirium in patients aged over 65 years.
Mathematical modeling of glucose regulation and sleep resting heart rate to predict risk of metabolic dysregulation in cancer survivors.
A physiologically informed mathematical model linking nocturnal glucose levels with resting heart rate dynamics provides a non-invasive, interpretable tool for early T2DM risk stratification based on nocturnal physiological patterns in cancer survivors.
Histamine H3 receptors in the paraventricular thalamus link sleep loss to fat overconsumption.
PVT-H3R signaling serves as a critical pathway converting circadian disruption to fat-specific hyperphagia, offering therapeutic targets for precise body-weight management.
Non-Invasive Contactless Tracking of Respiratory Rate and Heart Rate During Sleep.
Smart Bedding® IMU-based contactless monitoring accurately estimated respiratory and heart rates during sleep, achieving overall accuracies of 93.9% and 88.7% using zero-crossing and peak detection respectively, validated against polysomnography as the gold-standard reference.
Analysis of the trajectory of sleep quality changes and influencing factors in maintenance haemodialysis patients in Xinjiang, China: a prospective longitudinal study.
Latent class growth modelling identified four distinct heterogeneous sleep quality trajectories in maintenance haemodialysis patients, with depression as an overarching risk factor for unfavourable trajectories and pruritus and inflammation as specific predictors of persistent poor sleep.
Effect of 12 weeks with a 30-min nap opportunity during the night shift of healthcare workers on early cardiovascular risk biomarkers: the NAPWORK study protocol of a randomised controlled trial.
This paper presents a protocol for a 12-week randomised controlled trial investigating whether a 30-min nap opportunity during night shifts can reduce early cardiovascular risk biomarkers, including endothelial dysfunction, in healthcare workers.
The association between serum lipid metabolism and nightmares: insights from Mendelian randomization analysis of two samples.
Lipid metabolism characteristics have a causal relationship with nightmare risk, with higher triglyceride levels in HDL and LDL being protective and higher free cholesterol to total lipids ratio in medium LDL associated with increased nightmare risk.
Correlation Analysis of Nocturnal Noise with Melatonin Secretion and Bone Repair Factors in Patients with Osteoporotic Vertebral Compression Fractures.
Acoustic environmental modifications were associated with altered melatonin secretion patterns and changes in bone metabolism markers in patients with osteoporotic vertebral compression fractures.