Sleep

445 peer-reviewed studies indexed

Aging & Longevity 500 Sexual Health 498 Cardiovascular 497 Body Composition 496 Mental Health 475 Dietary Supplements 470 Hormone Therapy 469 Sleep 445 Exercise & Training 436 Gut Microbiome 417

Radar Multiple Bin Selection for Breathing and Heart Rate Monitoring in Acute Stroke Patients in a Clinical Setting.

Multiple range bin selection for radar-based monitoring yielded lower mean absolute errors and higher correlations with polysomnography reference for both breathing and heart rate in acute stroke patients, but provided lower temporal coverage compared to single range bin selection.

A nap can recalibrate homeostatic and associative synaptic plasticity in the human cortex.

A short afternoon nap recalibrates both homeostatic and associative synaptic plasticity in the human cortex, as evidenced by reduced net synaptic strength and increased inducibility of LTP-like plasticity following nap compared to wake.

Psychosocial pathways linking family support to sleep disorders in maintenance hemodialysis: the chain mediating role of depression and fatigue.

Family support influences sleep quality in MHD patients primarily through reducing depression and, secondarily, through a depression-fatigue pathway, with indirect pathways accounting for 64.2% of the total effect.

Effects of brisk walking and Tai Chi interventions on sleep quality in university students with insomnia.

Both Tai Chi and brisk walking are associated with significant reductions in global PSQI scores among university students with insomnia, indicating their potential as effective non-pharmacological interventions for improving sleep quality in this population.

Using Alcohol and Sleep Sensors to Understand Blackout Risk in Young Adults' Natural Settings (The Lights Out Study): Protocol for an Intensive Longitudinal Pilot Study.

This paper describes a protocol for a 14-day intensive longitudinal pilot study using wearable alcohol and sleep sensors combined with ecological momentary assessment to examine how other substance use and sleep behaviors are associated with alcohol-induced blackout risk in young adults.

The Impact of Environmental Stressors on Sleep Quality and Patient Experience in the Intensive Care Unit.

Perceived environmental stressors were significantly and negatively associated with both sleep quality and ICU experience, and poor sleep quality was itself a significant negative predictor of ICU experience, demonstrating both direct and indirect pathways through which environmental stressors contribute to negative critical care outcomes.

Stress, coping, and other determinants of poor sleep quality among healthcare students in a conflict region: a cross-sectional study.

Poor sleep quality is widespread among healthcare students in a conflict-affected context and is associated with increased stress, mental health issues, and avoidant coping, while regular physical activity was associated with better sleep quality.

Association between psychoeducational factors and perceived academic stress in medical students: a gender-based analysis.

Female medical students showed significantly higher levels of academic stress, overload, and exam anxiety than male students, with poor sleep quality identified as a significant factor associated with higher stress levels (OR = 1.12; 95% CI: 1.03–1.22) and female gender associated with a higher probability of reporting stress (OR = 5.56).

Developing a structured framework to explore the experiences of people with dementia and their caregivers regarding non-pharmacological sleep interventions.

A structured framework called DESMEE-CAP was developed through literature review, expert consensus, and co-creation to assess user experiences and monitor sleep and indoor environmental quality parameters for non-pharmacological sleep interventions in community-dwelling people with dementia and their caregivers.

Diurnal changes of cerebrospinal fluid and global signal coupling.

Coupling strength between global grey matter BOLD and CSF signals was highest in the morning and decreased significantly across the day, highlighting the importance of accounting for both the time of scan and individual sleep characteristics when interpreting fMRI-based gGM-CSF coupling measures.

Differences in Circadian Sleep Parameters as a Function of Gender in Patients on the Waiting List for Liver Transplantation.

Sex-specific differences in circadian sleep profiles were found among liver transplant candidates, with men exhibiting longer sleep duration, greater movement, and higher pre-sleep light exposure, whereas women demonstrated superior sleep efficiency and a delayed core sleep phase.

Physiological Effects of Far-Infrared-Emitting Garments on Sleep, Thermoregulation, and Autonomic Function Assessed Using Wearable Sensors.

FIR-emitting garments produced consistently lower tympanic membrane temperature, reduced mid-sleep sweating, and higher REM sleep proportion compared to control garments, indicating they 'facilitate mild nocturnal heat dissipation and support REM expression' as a passive intervention.

Prevalence of anxiety, depression and associated risk factors in gastroenterology outpatients: a multicenter cross-sectional study.

Anxiety and depression were prevalent among gastroenterology outpatients, with detection rates of 26.5% and 12.2% respectively, and were significantly associated with specific gastrointestinal diagnoses and poor sleep quality.

Excessive sleep duration increases the risk of dementia among older Chinese adults: evidence from the CLHLS.

Excessive sleep duration (over 10 hours) is an independent predictor of increased risk of dementia among older Chinese adults, while maintaining a moderate sleep duration of 6 to 8 hours appears to be a protective factor.

Improvement of nighttime gastroesophageal reflux symptoms with sleep positional therapy using a smartwatch app.

Sleep positional therapy using a smartwatch app that vibrates when patients lie in right lateral decubitus position significantly reduced nighttime gastroesophageal reflux symptoms and increased the number of reflux-free nights.

Patient outcomes and session dose in a randomized controlled trial of the Transdiagnostic Intervention for Sleep and Circadian Dysfunction: Influential factors and methodological considerations.

Participants who completed the recommended number of TSC sessions showed larger effect sizes and more significant improvements relative to usual care, and Kaplan-Meier analyses established that eight sessions optimized outcomes for Standard TSC and six sessions for Adapted TSC.

Sleep effects in drug-resistant epileptic patients taking perampanel: an observational study.

Perampanel appears to preserve sleep quality and mildly improve quality of life, and shows greater efficacy when used as a first add-on therapy in drug-resistant epilepsy.

[Impact of Anhui medical college students' childhood abuse experiences on depression and anxiety symptoms: The mediating role of mobile phone dependence and sleep quality].

Childhood abuse experiences can increase the risk of depression and anxiety symptoms in medical college students, and can also indirectly raise the level of depression and anxiety symptoms through the chain mediating role of mobile phone dependence and sleep quality.

Exploring comorbidity patterns of psychosis-related post-traumatic stress disorder and depression symptoms in stabilised hospitalised schizophrenia patients and relationships with sleep quality and quality of life: a latent profile analysis.

In hospitalised patients with schizophrenia, psychosis-related post-traumatic stress disorder and depression manifest in parallel patterns of low, moderate, or high severity rather than as distinct subtypes, with sleep quality progressively worsening as symptom severity increases.

Remote zero-burden sleep monitoring in veterans with PTSD and suicidal ideation: A longitudinal investigation of risk.

Aspects of sleep may be recorded in moderately suicidal persons using fully remote, zero-burden methods, with observed associations highlighting potential relevance to suicide surveillance and prevention.

Effects of sleep restriction on cognitive and physical performance in elite karate athletes: A randomized crossover study.

Partial sleep restriction (4 hours) substantially impairs both cognitive and physical performance in elite karate athletes, with compounding effects during exercise.

The Alzheimer's Pathways Sleep Study (ALPS): an experimental randomized controlled trial to improve cognition and Alzheimer's pathophysiology through slow-wave sleep.

The Alzheimer's Pathways Sleep Study (ALPS) is a randomized controlled trial testing whether a time-in-bed restriction intervention can increase slow-wave activity to improve cognition and Alzheimer's pathophysiology in older adults with poor sleep.

Disorder-specific alterations of transient oscillatory dynamics during sleep across cortical and subcortical networks.

Transient sleep oscillations show disorder-specific, trait-like microstructural alterations across cortical and subcortical networks in narcolepsy type 1, non-REM parasomnia, idiopathic REM sleep behavior disorder, and fibromyalgia syndrome, with slow oscillatory-power features supporting group-level discrimination in select EEG derivations.

Sleep quality and disturbance during the COVID-19 pandemic among people with HIV globally: associations with social determinants of health.

During the COVID-19 pandemic, 26.8% of people with HIV experienced decreased sleep quality and 27.1% experienced sleep disturbance, with social determinants of health including resource access and education level significantly associated with these outcomes.

The Effectiveness of the Headspace App for Improving Sleep: Randomized Controlled Trial.

Headspace can positively impact sleep quality, tiredness, and duration, as demonstrated by a randomized controlled trial showing improvements in both subjective and objective sleep outcomes over 8 weeks.

Association of Sleep Duration With Intracranial Atherosclerosis and Cerebral Small Vessel Disease: A Mediation by Metabolic Factors.

Aberrant sleep duration may increase the potential risk for intracranial atherosclerosis and cerebral small vessel disease, which can be partially mediated by blood pressure and fasting plasma glucose.

Exploring gender differences in the impact of sleep and fatigue on disease severity in rheumatoid arthritis: a moderated mediation model.

Fatigue fully mediates the relationship between poor sleep quality and disease severity in rheumatoid arthritis, and while female patients reported greater symptom burden, gender did not significantly moderate this mediation pathway.

Circadian rhythms and asthma: exploring the impact of circadian clock proteins on childhood asthma management.

Asthmatic children had significantly elevated levels of circadian clock proteins (BMAL1, CLOCK, CRY1, PER1, and PER2) compared to healthy controls, and these elevated levels correlated with poorer asthma control, reduced pulmonary function, and poor sleep quality, with PER2 and BMAL1 showing the highest individual diagnostic value (AUC ~0.75).

Ultra-short term Heart Rate Variability in moderate and severe Obstructive Sleep Apnea.

Ultra-short-term HRV varies with OSA severity, sleep stage, and type of respiratory event, with reduced HRV observed in severe OSA, NREM sleep, and during hypopneic events.

Sleep Quality and Its Determinants Among Patients with Metastatic Cancer Treated with Immune Checkpoint Inhibitors: A Two-Center Cross-Sectional Study.

Over half of patients treated with immune checkpoint inhibitors experienced clinically relevant sleep disturbance, with poor performance status, advanced disease burden, and later-line therapy independently predicting impaired sleep.

Joint associations of sleep duration and physical activity with functional limitations among Chinese older adults: A cross-sectional study.

Maintaining adequate sleep duration (6-8 hours) combined with high physical activity is associated with a significant reduction in the risk of functional limitations among Chinese older adults.

Association of Sleep Patterns with the Development of Idiopathic Scoliosis: A Nationwide Pediatric Cohort Study.

Later bedtimes and shorter sleep durations may contribute to idiopathic scoliosis development in children and adolescents, and these sleep pattern differences could partially explain the higher idiopathic scoliosis incidence observed in urban compared to rural students.

Sleepless Longing: Bidirectional Associations Between Sleep Quality and Prolonged Grief in Daily Life After Traumatic Loss.

These findings provide tentative support for a night-to-day, sleep-to-grief pathway, although both small effect sizes and variability in results underscore the need for replication in larger samples.

Distribution of device-measured 24-h movement behaviors in older adults: cross-sectional findings from the HUNT4 study.

This study provides novel insights into the distribution of 24-h movement behaviors among older adults, finding that participants spent 4.1 h standing, 82.8 min walking, 9.2 h sitting, and 7.1 h sleeping per day, with age, sex, and educational level influencing this distribution.

Gender Differences in Sleep Deprivation and Quality Among Spousal Caregivers of Disabled Partners: A Nationwide Cross-Sectional Study.

Caregiving for a disabled spouse impairs sleep among women but not men, and a clear graded relationship exists between care recipients' functional disability types and caregivers' sleep problems.

Influence of Ward Noise on Emotional State and Sleep Quality in Patients with Ventilator-induced Diaphragmatic Dysfunction.

Noise control care was associated with reduced anxiety and depression, improved sleep quality, and superior clinical outcomes in patients with ventilator-induced diaphragmatic dysfunction.

The relationship between mothers' maladaptive schemas and sleep problems in 12-to-36-month-old children: The role of attachment and sleep behaviors.

Mothers' early maladaptive schemas, particularly 'failure to achieve,' 'enmeshment/dependence,' and 'punitiveness,' were associated with sleep difficulties in children aged 12–36 months, with maternal age over 30 emerging as a strong risk factor and occasional partner/family support serving as a protective factor.

Seasonal and geographic variation in sleep duration among U.S. adults: Evidence from the 2022 BRFSS.

Geographic context, particularly time zone and latitude, plays a more consistent role than seasonality in shaping sleep duration in the U.S.

Joint Associations of Physical Activity and Sleep Quality With Cognitive Function Among Older Adults in China.

Both higher levels of physical activity and better sleep quality are important for cognitive health, with high-PA and good sleep quality showing the best global cognition and memory outcomes, supporting the need for dual-behavior interventions in aging populations.

Analysis of risk factors for frailty in older inpatients with interstitial lung disease.

Frailty prevalence among older inpatients with interstitial lung disease was 38.02%, with age, polypharmacy, poor sleep quality, and dyspnea identified as independent risk factors.

Cortical morphology of insomnia with objective short sleep duration phenotype.

The insomnia disorder subtype with objective short sleep duration (ISS) exhibited greater cortical thickness than the normal sleep duration subtype (INS) in multiple right-hemisphere regions, with negative correlations found between cortical thickness and total sleep duration.

Non-linear associations of blood volatile organic compounds (VOCs) with sleep health and mortality in American adults: data from the National health and nutrition examination survey (NHANES) 2007-2012.

VOC exposure may be linked to poor sleep patterns among U.S. adults, with non-linear associations observed between certain blood VOCs and sleep health indicators, and methyl tert-butyl ether identified as a risk factor for all-cause mortality.

The associations between sleep problems and physical exercise among Chinese university students: A network analysis of gender differences.

Network analysis of Chinese university students revealed gender-specific bridge nodes connecting sleep problems and physical exercise, with fatigue-exercise duration being the strongest connection in males and difficulty falling asleep-exercise frequency in females.

Misperception of supine sleep in the sleep laboratory: a retrospective review of self-reported versus polysomnography-measured sleep position.

Patients denying supine sleep in the laboratory were more likely to misperceive sleep position on PSG, with younger females under-reporting supine sleep, and overall agreement between self-reported and polysomnography-measured sleep position was only moderate.

Network Structure of Sleep Quality and Emotional State Among ICU Nurses: A Cross-Sectional Analysis.

This study reveals a bidirectional network linking sleep and emotional symptoms in ICU nurses, identifying anxiety and subjective sleep quality as central nodes, with fatigue and sleep disturbances as key bridges.

[Infant sleep patterns based on latent class analysis and their influencing factors].

Infant sleep patterns are influenced by multiple factors; increasing outdoor activity and limiting screen exposure help infants form good sleep patterns.

Effects of paroxetine combined with low-dose quetiapine on stress response and endocrine function in patients with treatment-resistant depression and sleep disorders.

Paroxetine combined with a low dose of quetiapine is a clinically effective approach for treatment-resistant depression with sleep disorders, demonstrating superior efficacy over paroxetine alone in depression/anxiety scores, sleep quality, stress response, and endocrine function.

Noradrenergic activity as a key target in modulating consciousness.

Noradrenergic activity selectively modulates conscious (but not unconscious) neural processing, making it 'a key target for pharmacological manipulations of consciousness.'

Differentiating bipolar disorder and schizophrenia using sleep EEG power and coherence features: A machine learning approach based on polysomnography.

A random forest classifier integrating overnight polysomnography EEG power spectral and coherence features achieved 71.88% accuracy and ROC-AUC of 0.770 in distinguishing bipolar disorder from schizophrenia, with F3_Theta_Pow, total wake time, C3_Theta_Pow, and sleep efficiency emerging as the most discriminative features.

Nabiximols improves sleep architecture in multiple sclerosis: A prospective polysomnographic study.

A prospective polysomnographic study found significant sleep disruption in people with multiple sclerosis compared to healthy controls, and a 6-week nabiximols trial resulted in significant improvement in both patient-reported and objective polysomnographic sleep measures.