Cardiovascular
497 peer-reviewed studies indexed
Exploring the Application Value of Magnetocardiography in Detecting Pulmonary Hypertension: A Noninvasive and Visual Approach.
Magnetocardiography demonstrates highly promising potential for the noninvasive detection of pulmonary hypertension, achieving sensitivity of 86.1% and specificity of 94.1% in a testing cohort, and can detect PH in patients with normal ECG findings.
Ethnicity and Heart Failure Outcomes in England: Role of Specialist Care in a Universal Health System.
In a universal health care system, treating an ethnically diverse population hospitalized for HF, non-White patients received better pharmacological management, which was associated with better long-term outcomes.
Synergistic effects of combined breathing training and aerobic exercise on cardiopulmonary function in chronic heart failure: a systematic review and meta-analysis.
Breathing training combined with aerobic exercise has positive effects on pulmonary function, cardiopulmonary exercise capacity, and quality of life in patients with chronic heart failure, while its impact on cardiac function parameters appears to be limited.
Efficacy and Safety of Sacubitril/Valsartan After Switching From Azilsartan in Essential Hypertensive Patients: Based on Home Blood Pressure Monitoring.
Sacubitril/valsartan was generally well tolerated and effectively controlled out-of-office blood pressure and decreased NT-proBNP after switching from azilsartan in essential hypertensive patients.
Factors Influencing Self-Care Among Patients With Heart Failure Based on the Situation-Specific Theory: A Cross-Sectional Study.
Health literacy, self-efficacy, symptom experience, and social support were key predictors of self-care among patients with heart failure, with final regression models explaining 39.4%, 31.0%, and 44.1% of variance in self-care maintenance, symptom perception, and self-care management, respectively.
[Effect of ZHU Lian's acupuncture stimulation method on neurological function in rats with ischemic stroke based on the miR-34a-5p/YWHAG pathway].
ZHU Lian's acupuncture stimulation method could improve neurological function in IS model rats, possibly by modulating the miR-34a-5p/YWHAG pathway.
[Effect of Tongdu Tiaoshen acupuncture on hippocampal neuronal synaptic remodeling in rats with post-stroke depression based on the CCL2-CCR2 pathway].
Tongdu Tiaoshen acupuncture could improve neurological function and depressive-like behavior in PSD rats, possibly by inhibiting the CCL2-CCR2 pathway and promoting neuronal synaptic remodeling in the hippocampus.
EFFECTS OF FARICIMAB LOADING PHASE ON DIABETIC MACULAR EDEMA IN REAL-WORLD SETTING: An Optical Coherence Tomography Angiography Study.
Faricimab loading phase showed promising results in visual outcomes and structural improvement in resistant diabetic macular edema.
Preference, Awareness, and Use of Sphygmomanometers in the Mercury-Free Era: A Cross-Sectional Survey of Physicians in Korea.
Despite regulatory restrictions following the mercury ban, 12.8% of Korean physicians continued to use mercury sphygmomanometers, awareness of mercury-free BP devices remained suboptimal (50.3% above-average awareness), and compliance with standardized BP measurement protocols was variable, indicating a need for comprehensive education.
Statin prescription rates for prevention of atherosclerotic cardiovascular disease in adults 40-75 years old with type 1 diabetes.
Notable gaps exist in statin prescribing and LDL goal attainment among adults with type 1 diabetes aged 40-75 years, with only 43.2% prescribed guideline-recommended statin therapy and female sex independently associated with lower odds of receiving guideline-recommended statin therapy and achieving LDL targets.
Individualised Empowerment in Secondary Cardiac Rehabilitation in Patients With Coronary Heart Disease: A Qualitative Study.
Five themes emerged from young and middle-aged coronary heart disease patients' experiences in secondary cardiac rehabilitation, consistent with all dimensions of health empowerment theory, emphasising the importance of individualised empowerment for improving cardiac rehabilitation intervention programmes.
Multilingual Video Education for Hospitalized Patients With Myocardial Infarction (EDUCATE-MI): Single-Arm Implementation Study.
A short multilingual educational video may improve patient knowledge of myocardial infarction before discharge, with mean correct responses increasing from 5.4 to 7.2 out of 10 (mean difference=1.9, 95% CI 1.6-2.2; P<.001; Cohen drm=0.72).
The relationship between the atherogenic index of plasma and hyperuricemia in American adults aged over 20 years: A cross-sectional study.
AIP and the risk of HUA demonstrated an inverted L-shaped positive association in the adult US population, with the association stronger in females than in males.
Quality of Life Assessment in Heart Failure Patients: Insights from a Low- to Middle-Income Country.
Good QoL was observed in only one-fourth of patients living with HF, with older age (>70 years), presence of diabetes, and non-adherence to medication independently associated with poorer QoL.
The Influence of Dietary Habits and Physical Activity on Quality of Life of Peripheral Arterial Disease in Patients Hospitalized at the Department of Vascular Surgery and Transplantation, Medical University in Białystok.
Lifestyle interventions for PAD patients should consider educational level and age-related decrease in physical activity, as physical activity is significantly associated with the physical component of quality of life, while intensifying physical activity or supplementation is not necessarily associated with improvement of mental wellbeing.
Provider networks for pulmonary hypertension in Massachusetts: implications for improving referrals to expert care.
Few providers caring for patients with pulmonary hypertension were connected to PH experts, with significant gaps driven by provider specialty, geographic location, and limited PH panel volume, suggesting multifaceted strategies are needed to improve referral rates.
BACH2 ameliorates cell apoptosis and autophagy as a molecular switch of BCL-2/Beclin-1 complex in myocardial infarction.
BACH2 functions as a molecular switch by transcriptionally promoting BCL2 expression and the formation of the BCL2/Beclin-1 complex, thereby inhibiting both cardiomyocyte apoptosis and autophagy during myocardial infarction, and the natural compound Myricetin activates BACH2 to protect the heart in a BACH2-dependent manner.
Liver disease in management and outcomes of European and Asian patients with atrial fibrillation: A report from two observational prospective registries.
In atrial fibrillation, liver disease is associated with reduced OAC prescription (especially in Europe) and a higher risk of adverse outcomes, particularly in patients not receiving OAC, with no significant differences in outcome risks between European and Asian cohorts.
Inflammatory markers associated with albuminuria and early atherosclerosis in type 2 diabetic kidney disease: a cross-sectional study.
Albuminuria was positively associated with heightened systemic and cellular inflammation, and exploratory mediation analyses suggested that inflammatory pathways—particularly IL6, IL1β, and TLR2—may partly account for the association between albuminuria and subclinical atherosclerosis in type 2 diabetic kidney disease.
Stroke risk assessment in children with sickle cell disease using transcranial Doppler ultrasound in Cameroon.
Approximately 8.2% of children with sickle cell disease in Cameroon showed high cerebral artery velocities indicating elevated stroke risk, with acute chest infections potentially exacerbating risk and prophylactic vaccination potentially protective.
Nailfold capillaroscopy improves cardiovascular risk stratification in SSc: an adjustment of the SCORE2 algorithm.
Incorporating baseline nailfold capillaroscopy findings into the SCORE2 algorithm improves cardiovascular risk stratification in patients with systemic sclerosis and may support more individualized cardiovascular prevention strategies.
Clinical and Pathological Features of Vasculitic Neuropathy: A Single-Center Study in China.
This first large cohort of vasculitic neuropathy in mainland China delineates its clinical-pathological features, finding that nerve biopsy remains the diagnostic gold standard and that overall prognosis is relatively favorable with a 5-year all-survival rate of 80.23%.
[Burden, trends and gender disparities of alcoholic cardiomyopathy in China from 1990 to 2021].
From 1990 to 2021, the disease burden of alcoholic cardiomyopathy in China increased significantly, driven jointly by epidemiological factors, population aging and population growth, with marked disparities in gender and age distribution, identifying middle-aged and elderly males as the high-burden population.
Changes in Systemic Inflammatory Marker Levels Following Percutaneous Revascularisation of Lower Extremity Arteries.
Endovascular femoropopliteal revascularisation induces distinct short-term inflammatory responses, with IL-6 showing the most pronounced peri-procedural dynamics, and restored limb perfusion may modulate systemic inflammation at three months.
Severity and distribution of coronary artery disease in lebanese patients undergoing coronary angiography: Impact of gender and age on angiographic characteristics, a cross-sectional study.
Gender and age are associated with distinct angiographic patterns of CAD, with male gender linked to more extensive coronary disease and older age associated with greater comorbidity burden and impaired ventricular function in Lebanese patients.
[Treatment with inhaled nitric oxide in patients with pulmonary embolism].
Inhaled NO therapy in complex therapy of PE demonstrated safety and efficacy in relation to clinical, functional and laboratory parameters in patients with moderate-low-risk pulmonary embolism.
Prevalence of dyslipidaemia and low-density lipoprotein cholesterol target attainment: a descriptive cross-sectional study among adults in the Western Province of Sri Lanka.
Three-fourths of adults in Western Province, Sri Lanka had any form of dyslipidaemia, more common in females, with low HDL-C as the most frequent abnormality, and most participants aged above 40 years were at low cardiovascular risk yet two-thirds failed to meet LDL-C targets.
Ileus causing STEMI electrocardiographic findings.
Gastric and jejunal loop dilation caused ST-segment elevation in inferolateral leads mimicking STEMI, which resolved after gastric decompression, suggesting cardiac external compression as the mechanism.
LLM-Powered Dysphagia Screening With Multimodal Physiological Signal Analysis and Medically Informed Prompts.
An LLM-based framework integrating multimodal physiological signals (laryngeal vibration, nasal airflow, and swallowing sound) with medically-informed prompts achieves 96.3% classification accuracy for dysphagia screening, outperforming baseline models and maintaining robust performance in few-shot learning settings.
Machine Learning-Based Risk Prediction for Coronary Heart Disease Complicated by Hyperhomocysteinemia: Retrospective Study.
The LightGBM model demonstrated high accuracy and interpretability in forecasting CHD risk among patients with HHcy, with age and activated partial thromboplastin time identified as the most influential predictors via SHAP analysis.
Effect of ondansetron on QTc interval prolongation in healthy pediatric patients: a systematic review and meta-analysis.
There was a statistically significant increase in QTc and Tp-e intervals following ondansetron administration in healthy pediatric patients, however it is highly unlikely that these changes result in cardiac dysrhythmia, suggesting no relationship between low-dose ondansetron use and an increased risk of dysrhythmia in healthy pediatric patients.
Real-world effectiveness and safety of torsemide and spironolactone fixed dose combination in Indian heart failure patients (RESTORE-HF study): a prospective, multicenter, observational study.
The RESTORE-HF study demonstrated that the torsemide-spironolactone fixed-dose combination may be associated with a mean body weight reduction of 2.41 kg and may be generally well-tolerated in Indian heart failure patients, with significant symptomatic improvement over 3 weeks in real-world clinical practice.
Cardiorespiratory fitness attenuates the association between psychosocial stress and cardiometabolic risk - Results from the SCAPIS population.
Higher cardiorespiratory fitness attenuated the association between psychosocial stress and cardiometabolic risk, with associations between CRF and cardiometabolic risk being 13-25% stronger in the high-stress group.
An evaluation of age-varying genetic effects underlying body-mass index and blood pressure in the UK Biobank.
Age-stratified GWAS in UK Biobank identified differential enrichment of age-interaction effects that were trait-dependent, with downstream MR analyses highlighting the influence of age on the genetically predicted relationship between pulse pressure and adverse cardiovascular outcomes.
Effects of music therapy in patients with diabetic retinopathy undergoing pan‑retinal photocoagulation.
A three-phase music therapy intervention is a safe and effective approach for reducing procedural pain, anxiety, and blood pressure in patients undergoing pan-retinal photocoagulation.
Effect of CT Section Thickness on Aortic Valve Calcium Scoring via Photon-counting Detector CT.
Thin-section PCD CT decreased AVAS and AVCV, resulting in AS severity reclassification in 8%-9% of patients.
Impact of Obesity on Patients with Resistant and Refractory Arterial Hypertension: A Cross-Sectional Study.
In a population of patients with severe hypertension, obesity was prevalent and significantly influenced both the presentation and the control of blood pressure levels, with higher BMI directly associated with an increased number of antihypertensive medications required for blood pressure control.
Machine Learning Integrates Bulk and Single-Nucleus RNA Sequence to Explore Apoptosis-Related Gene in Myocardial Infarction.
Multiomics integration of snRNA-seq and bulk RNA-seq with machine learning identified TNFRSF12A as a key regulator of apoptosis-related gene activation in myocardial infarction, with fibroblasts demonstrating significantly elevated apoptotic activity compared with other cardiac cell types.
Genetic and Clinical Characterization of a South-Brazilian Hypertrophic Cardiomyopathy Cohort.
This study offers the first detailed genetic and clinical characterization of a Brazilian HCM cohort using massive parallel sequencing, finding MYH7 and MYBPC3 as the most frequently implicated genes and underscoring the importance of genetic testing for diagnosis, risk stratification, and management.
Impact of Basal Ganglia Perivascular Spaces on Ischemic and Hemorrhagic Risks in Patients Taking Antithrombotic Therapies.
Higher basal ganglia-enlarged perivascular space burdens are associated with higher risks of ischemic stroke and major bleeding in patients receiving antithrombotic therapy, suggesting BGPVSs may serve as useful imaging biomarkers for vascular risk assessment and personalized therapy.
Standardizing the Clinical Approach to Cancer Therapy-Related Cardiac Dysfunction: Applying Cardio-Oncology Guidelines as a Practical Tool for Hematology and Oncology Providers.
A multidisciplinary cardio-oncology expert panel developed a consensus statement providing practical, case-based guidance to help oncology providers recognize, assess, and manage cancer therapy-related cardiac dysfunction (CTRCD) by applying evidence-based recommendations from current ESC and ICOS guidelines.
Acute oncology hospital care at home for post-chemotherapy monitoring.
Hospitalization at home demonstrated non-inferiority for healthcare utilization compared to standard inpatient monitoring among patients with multiple myeloma receiving DCEP±V chemotherapy, with 92% successful HaH admissions and 208.8 inpatient bed-days saved.
Cardiovascular health assessed by Life's Essential 8 score, genetic risk, colonoscopy status, and risk of colorectal cancer: an analysis of UK Biobank.
Better cardiovascular health assessed by Life's Essential 8 score is associated with a reduced risk of colorectal cancer, particularly in individuals with high genetic susceptibility and those without a history of colonoscopy screening.
Evaluation of Supracardiac Atherosclerosis in Stroke with a Noncontrast Head-Neck-Aortic Vessel Wall MRI.
A noncontrast head-neck-aortic vessel wall MRI protocol demonstrated a higher plaque detection rate than supra-aortic CTA and enabled reclassification of 42% of ESUS patients, reducing the ESUS percentage from 35.2% to 20.4%.
Deep Learning-based Monoenergetic Imaging for Calcified Coronary Stenosis Assessment at Energy-integrating Detector CT.
DIAMOND demonstrated feasibility of generating high-kiloelectron volt virtual monoenergetic images from single-energy energy-integrating detector CT, providing artifact-reduced coronary imaging and improved stenosis quantification for heavily calcified plaques comparable to photon-counting detector CT without hardware upgrades.
Association Between Depression and Increased Odds of Inpatient Mortality Following Hip Fracture Repair.
Patients with depression experienced increased odds of adverse events during their hospitalization including inpatient mortality, DVT/PE, and myocardial infarction following hip fracture repair, and were less likely to experience routine discharge with longer length of stay and greater total charges.
Smartphone Cardiac Rehabilitation, Assisted Self-Management (SCRAM) Versus Usual Care: Multicenter Randomized Controlled Trial.
SCRAM did not lead to a clinically important difference in VO2max compared to usual cardiac care in this underpowered trial, but was resilient to COVID-19-related disruptions that significantly impacted the delivery of cardiac rehabilitation.
Repair of Asymmetric Bicuspid Aortic Valve Using Tricuspidation with CardioCel.
A novel tricuspidation technique for asymmetric bicuspid aortic valve repair using CardioCel bovine pericardium neo-cusps resulted in all 15 patients alive with well-functioning valves presenting no or trivial insufficiency, large orifice areas, and nearly physiological transvalvular gradients.
Comparative Predictive Validity of Fall-Risk Screening Assessments in Subacute Stroke.
No single test emerged with strong discriminative power for predicting future falls at discharge from inpatient rehabilitation for stroke, but a combination of gait speed, STOB, and FGA may enhance prognostic decision-making accuracy.
Iatrogenic Cerebral Amyloid Angiopathy After Cardiac Surgery: Two Case Reports.
Two patients with early-onset cerebral amyloid angiopathy after cardiac surgery using cadaveric dura mater patches are described, adding to evidence of Aβ transmissibility in humans and demonstrating that iatrogenic CAA risk extends beyond neurosurgical procedures.