Cardiovascular
497 peer-reviewed studies indexed
Using Interpretable Machine Learning with SHAP to Assess Dynapenic Abdominal Obesity as a Stroke Risk Predictor: A Prospective Cohort Study.
Dynapenic abdominal obesity (DAO) was independently associated with increased stroke risk (adjusted OR = 1.58, 95% CI: 1.21–2.06) in middle-aged and older Chinese adults, with interpretable machine learning (XGBoost, AUC = 0.92) further supporting its potential as a stroke predictor.
Clinical use of reserved guide wire fenestration and Viabahn-covered stent in Stanford type B aortic dissection with left subclavian artery involvement.
External stent fenestration with a reserved guide wire and Viabahn-covered stent demonstrated significant efficacy in treating Stanford type B aortic dissection involving the left subclavian artery, achieving full technical success with no postoperative deaths, minimal complications, and shorter hospital stay versus the conventional in-situ fenestration approach.
Feasibility of the extended, 48-h ambulatory blood pressure monitoring in hemodialysis patients: a multicenter study.
48-h ABPM is feasible in only about half of hemodialysis patients, with discomfort and sleep disturbance being the most frequently cited reasons for refusal and important barriers to both acceptance and completion.
Clinical outcomes of arterial detection ligation technique for grade II/III versus grade IV hemorrhoidal disease.
ADL-mucopexy demonstrated comparable short-term clinical outcomes and patient satisfaction across different HD grades, suggesting it may be considered a potential minimally invasive surgical option in carefully selected patients with grade IV HD.
Application of new media-based home nursing intervention for stroke-related depression patients: a retrospective cohort study.
Family-centered new-media continuous nursing is associated with improved functional independence, psychological recovery, adherence behaviors, and favorable biological changes in patients with ischemic stroke.
Association between C-reactive protein to triglyceride-glucose index and atrial fibrillation: a cross-sectional analysis.
A higher CTI (C-reactive protein to triglyceride-glucose index), reflecting combined elevated inflammation and insulin resistance, is significantly and independently associated with an increased prevalence of atrial fibrillation (OR 7.27, 95% CI 5.87-9.00).
Geometric Decomposition of OCT Angiography in RVO: Unmasking Congestive Versus Compensatory Phenotypes and Deep Retina-Choroid Coupling.
Morphologic decomposition of vessel density into vessel length density and vessel diameter index reveals subclinical compensatory remodeling in fellow eyes obscured by conventional analysis, and progressive synchronization of deep retinal and choroidal degeneration suggests RVO involves a pathologic collapse of neurovascular autoregulation.
Risk Factors for Infective Endocarditis in Contegra Grafts Used as Right Ventricle-Pulmonary Artery Conduits: A Retrospective Cohort Study.
IE occurred in 6.3% of patients after Contegra implantation, and higher conduit peak velocity with turbulent flow on immediate postoperative echocardiography was associated with an increased IE risk.
Delayed anti-vascular endothelial growth factor therapy in patients with type 2 diabetes mellitus and branch retinal vein occlusion-associated macular edema negatively affects visual outcomes.
Initiation of anti-VEGF therapy within seven days of diagnosis is associated with greater six-month visual improvement in patients with BRVO-ME and T2DM, and delayed treatment may contribute to suboptimal visual recovery.
Real-world safety assessment of avacopan in patients with antineutrophil cytoplasmic antibody-associated vasculitis.
Avacopan demonstrated a favourable safety profile in patients with AAV in real-world settings, with 8 positive SOC signals and 92 positive PT signals identified, and hepatobiliary events being the leading adverse events particularly among geriatric and female patients.
Timing matters: early antiplatelet therapy optimizes alteplase treatment in acute ischemic stroke.
Initiating antiplatelet therapy within 24 hours after alteplase improves neurological and functional recovery in acute ischemic stroke without increasing hemorrhagic risk.
[Development and Validation of a Risk Prediction Model for Secondary Pulmonary Infarction in Elderly Patients With Acute Pulmonary Embolism].
A risk prediction model incorporating alcohol consumption, chronic bronchitis, emphysema, coronary heart disease, diabetes, and D-dimer demonstrated high discriminatory power (AUC 0.936) and accuracy for predicting secondary pulmonary infarction in elderly patients with acute pulmonary embolism.
Endovascular repair of descending aorta lesions using a second-generation unibody single-branched stent-graft: a technical note.
The Cratos single-branched stent-graft provides a safe and effective option for one-stage endovascular repair of aortic arch pathologies requiring zone 2 landing, achieving complete exclusion of the entry tear and preservation of LSA flow without endoleak or neurological complications.
Role of sodium glucose cotransporter-2 (SGLT2) inhibitors in the modulation of QTc interval and ventricular arrhythmia in patients with diabetes mellitus combined with hypertension and coronary artery disease.
SGLT2 inhibitors effectively shorten QTc interval, reduce ventricular arrhythmia and cardiovascular risks in DM-HTN-CAD patients and show favorable safety for clinical reference.
Cross-sectional analysis of periodontitis and peripheral artery disease association: Results from National Health and Nutrition Examination Survey 1999 to 2004.
Analysis of a nationally representative American population reveals periodontitis as an independent predictor of heightened PAD probability, with periodontitis maintaining independent association with PAD (OR=1.49; 95% CI:1.04-2.13) after comprehensive covariate adjustment.
16S rRNA Metabarcoding Used to Identify the Etiology of Infective Endocarditis Agents.
16S rRNA metabarcoding demonstrated efficiency in identifying bacterial agents in native cardiac valves affected by infective endocarditis compared to routine noninvasive diagnostic methods, revealing numerous opportunistic pathogenic bacteria including in negative blood culture cases.
Remote Augmented Reality Versus Traditional Simulation for Team Leader Assessment in a Cardiac Arrest Scenario: Noninferiority Randomized Controlled Trial.
Remote AR simulation demonstrated noninferior team leader decision-making and behavioral performance compared with traditional in-person simulation for assessing cardiac arrest leadership, suggesting it 'may be a viable strategy to expand access to scenario-based assessment of cardiac arrest leadership, particularly in resource-limited settings.'
The impact of ai r q ua l ity index (AQI) and par tic ulate mat ter 2.5 (PM ) c oncen tration on the incid en ce of st roke i n Karachi, Pakist an : A bidirec tion al cohor t st ud y.
Short-term rise in air quality index readings and particulate matter 2.5 concentrations were found to have no association with the incidence of ischaemic and haemorrhagic strokes in Karachi, Pakistan.
Clinical value of the fibrosis-4 index in predicting decompressive craniectomy after mechanical thrombectomy in stroke.
The FIB-4 index emerged as a significant and independent prognostic marker for identifying patients at risk of requiring decompressive surgery following mechanical thrombectomy for acute ischemic stroke.
Neurodevelopmental outcomes in preschool children with congenital heart defects: A case-control study using Ages & Stages Questionnaire.
The overall ASQ score in children with surgically corrected CHD was comparable to controls, however cases had five-fold increased odds of a low score, primarily driven by children with prenatally undetected VSD.
Safety and efficacy of direct versus conventional transfer to angiography suite in patients with severe acute stroke treated with thrombectomy (DIRECT ANGIO) in France: a multicentre, open-label, blinded-endpoint, randomised controlled trial.
Direct transfer to angiography suite for patients with acute severe neurological deficit highly suggestive of large vessel occlusion was associated with an increased risk of symptomatic intracranial haemorrhage without evidence of a beneficial effect on functional outcome at 90 days.
Tunisia's Heartbeat : Pioneering Isotopic Techniques in Cardiac Viability Among Resource Challenges.
Myocardial viability scintigraphy proved to be a highly reliable tool comparable to 18FDG PET-CT that significantly influenced therapeutic decisions and provided prognostic information in Tunisian patients with ischemic heart disease.
Ultrasound-derived tibia-fascia angle for noninvasive assessment of intracompartmental pressure in tibial plateau fractures.
Ultrasound-derived tibia-fascia angle difference (ΔTFA) showed a significant linear correlation with intracompartmental pressure and achieved moderate diagnostic accuracy (AUC 0.716) as a noninvasive screening tool for high compartment pressure in tibial plateau fractures.
Usability Evaluation of a Macular Quantitative Square Grid Self-Examination Application in Patients With Macular Disease: Mixed Methods Study.
The GridMacuScan application demonstrated diagnostic sensitivity comparable to that of the traditional Amsler grid and received high user ratings for usability, with a mean SUS score of 82.1 indicating 'good-excellent' usability.
Hemolytic anemia post high-dose IVIG in Kawasaki disease: Impact of inflammation and iron status on outcomes.
Fifteen percent of Kawasaki disease patients treated with IVIG developed hemolytic anemia, with non-O blood group, higher cumulative IVIG dose, elevated NT-ProBNP levels, and increased white blood cell counts significantly associated with increased risk of hemolysis.
Gender and racial disparities in the treatment of carotid artery stenosis.
Carotid disease incidence, prevalence, treatment and outcomes differ by gender and race, and next steps for research are needed to eliminate these disparities.
[Association between right ventricular function and short-term death risk in patients with sepsis].
Right ventricular dysfunction is common in patients with early sepsis and serves as an independent risk factor for 30-day death.
Effect of Metformin in Diabetic Patients After Treatment of Intracranial Aneurysm: A Nationwide Cohort Study.
Metformin use in diabetic patients treated with clipping or coiling for intracranial aneurysm was associated with reduced risk of subarachnoid hemorrhage (adjusted hazards ratio, 0.63; 95% CI, 0.41-0.95; P = 0.028).
Orientin Mitigates High Glucose/Ox-LDL-Triggered Endothelial Cell Injury and Atherosclerosis by Regulating MARCH8-Mediated NLRP3 Inflammasome Activation.
Orientin alleviates endothelial cell inflammation and pyroptosis through regulating the MARCH8/NLRP3 axis and might be a potential candidate for treating diabetes-accelerated atherosclerosis.
Labour-type physical activity, metabolic dysregulation, and hypertension in rural older adults: rethinking work, exercise, and health in a cold-climate agricultural community.
In a cold-climate rural Chinese cohort of older adults, higher labour-type physical activity volume and worse metabolic-obesity phenotypes were independently associated with higher odds of prevalent hypertension, inconsistent with the assumption that 'work equals exercise.'
The relay single-branched stent graft for distal aortic arch repair: mid-term single-center results.
The Relay™ single-branched endograft demonstrated excellent technical success and favorable neurological outcomes in patients with distal arch disease, supporting its use as a safe alternative to more complex branched configurations in anatomically suitable patients.
Prevalence of anemia in patients with chronic kidney disease attended at a nephrology outpatient clinic and its association with the outcome of renal replacement therapy over five years: a retrospective cohort study, Municipality of São Paulo, 2010-2018.
A high prevalence of anemia (41.8%) was found in chronic kidney disease patients from Primary Health Care, and anemia at admission was associated with a higher risk of progression to renal replacement therapy over five years (HR 3.24; 95%CI 1.38–7.61).
Physical activity modifies the association between dietary fiber and hypertension: A cross-sectional study of U.S. adults from NHANES 2007-2018.
The protective association of dietary fiber with hypertension was observed primarily in highly active adults, but not in less active individuals, highlighting the importance of the diet-activity interplay for hypertension prevention.
Diabetic retinopathy severity is associated with renal function deterioration in patients with diabetic kidney disease: a retrospective cohort study.
DR severity was independently associated with the progression of DKD, whereas HEs were not, with PDR and NPDR each presenting a nearly threefold greater risk of renal function deterioration compared with absent DR.
Assessing the Impact of a Training Intervention on Venous Compression Bandaging Application: A Factorial Design Randomised Trial.
A one-hour behaviourist-based training intervention did not significantly improve compression bandaging quality (CCB score) among advanced practice nursing students, and improvements observed at one month were not sustained at three months.
[Mortality trend of myocardial infarction and its age-period-cohort effects in permanent residents in Hebei Province, 2014-2022].
The MI mortality rate in permanent residents in Hebei showed an upward trend from 2014 to 2022, with men generally having higher mortality than women, indicating that prevention and control of MI is still challenging.
Association of the Endothelial Activation and Stress Index (EASIX) with short-term mortality in critically ill patients with congestive heart failure: A retrospective cohort study from the MIMIC database.
EASIX is a robust predictor of short-term mortality in patients with critical CHF, with the highest quartile exhibiting a 60% increased mortality risk beyond conventional severity scores.
The influence of polymorphisms in cytokine genes on pain and response to palliative radiotherapy in multiple myeloma patients: prospective observational study.
Polymorphisms in cytokine genes, specifically IL1RN rs2234677, IL1A rs1800587, IL1B rs1143634, and IL1RN rs315952, significantly influenced pain severity and response to palliative radiotherapy in multiple myeloma patients.
Clozapine-Induced Myocarditis in Huntington's Disease: Case Report.
A 51-year-old male with Huntington's disease developed acute myocarditis during clozapine treatment initiated for psychotic symptoms, highlighting the vital importance of early cardiac monitoring during clozapine use, particularly in psychiatric conditions accompanied by neurodegenerative processes.
TIE2 links MEKK3-KLF2/4 and PI3K signaling in cerebral cavernous malformation.
TIE2 is identified as the molecular link between MEKK3-KLF2/4 and PI3K signaling pathways during CCM formation, and targeting TIE2 provides almost complete rescue of CCM formation in mouse models.
Comparative Effect of Ticagrelor and Clopidogrel on Left Ventricular Remodeling in Acute Coronary Syndrome Patients: A Retrospective Cohort Study.
Ticagrelor was associated with more favorable LV remodeling parameters compared with clopidogrel in ACS patients post-PCI, including greater reductions in LVEDV, LVESV, and BNP, and greater improvement in LVEF.
Cardiac Rhythm and Conduction Abnormalities in Aircrew.
This paper presents current benchmark recommendations for assessing aircrew with rhythm and conduction abnormalities, derived from aeromedical and clinical literature and expert consensus of NATO Working Groups on Occupational Cardiology.
Cost-effectiveness of implementing a home blood pressure telemonitoring program.
The HBPT program in a real-world clinical setting achieved modest BP reductions, although overall costs increased primarily due to enrollment expenses.
Short-Term Arrhythmia Prediction Using AI Based on Daily Data From Implantable Devices: Multicenter Prospective Observational Study.
An AI model using 31-day records from implantable device remote monitoring data was capable of predicting short-term increases or decreases in arrhythmic episodes with global sensitivity of 66.4% and specificity of 77.4%.
Impact of Coronary Microvascular Dysfunction on Left Ventricular Function After Percutaneous Coronary Intervention: Assessment With Combined Dipyridamole-Exercise Stress and Myocardial Strain/Work.
Combined dipyridamole-exercise stress echocardiography with myocardial strain/work analysis effectively evaluates LV function in CMD, with decreased CFVR post-PCI associated with impaired LV function and worse 1-year quality of life outcomes.
Analysis of the Phenotype and Gene Mutations of Two Families With Combined Mutations of Anticoagulant Protein Genes.
Dual mutations in SERPINC1 and PROC genes confer markedly increased VTE susceptibility, with compound heterozygous mutations identified in two pedigrees showing decreased anticoagulant protein activity and impaired plasma anticoagulant function on thrombin generation assays.
Free Triiodothyronine as a Biomarker for Ventricular Arrhythmia Following Myocardial Infarction: A Multicenter Prospective Cohort Study.
Low plasma free triiodothyronine (FT3) levels are independently associated with an increased risk of ventricular arrhythmias during hospitalization in patients with acute myocardial infarction.
[PONTE-HF/ACS registry: optimization of medical therapy in outpatient clinics in Apulia for patients with heart failure].
The PONTE-HF/ACS registry shows good optimization of therapy in enrolled patients with HFrEF, highlighting the quality of care provided by the HF outpatient network in the Apulia region.
[Medium- and long-term clinical efficacy of tibial transverse transport surgery in the treatment of diabetic foot ulcers].
TTT surgery applied in treating patients with DFU can significantly improve lower limb blood supply and foot microcirculation, alleviate pain, and enhance nerve conduction function and foot sensation, with few postoperative complications and remarkable results in wound healing and limb salvage, maintaining good overall efficacy within 3 years after surgery.
Analysis of 6-week mortality and influencing factors in patients with liver cirrhosis and portal vein thrombosis complicated by acute gastrointestinal bleeding.
Elevated ALP and 5-day treatment failure were found to be independent risk factors for 6-week mortality in patients with cirrhosis and portal vein thrombosis complicated by acute gastrointestinal bleeding.